Pierce A, Wilson D, Wiebkin O
Int J Oral Maxillofac Surg. 1987 Jun;16(3):338-45. doi: 10.1016/s0901-5027(87)80156-x.
Previous reports have demonstrated that Surgicel, a local haemostatic agent, is absorbed from implantation sites. In an earlier study, it was shown that the material consists of a uronic acid component and a fibrous residue. A chemically quantified loss of the uronic acid component within 18 h of implantation was demonstrated. The aim of the present study was to examine the fate of the fibrous residue in rat tissues, using both light and electron microscopy. Results indicated that this fibrous component is phagocytosed by macrophages at the site of implantation. A model for the clearance of Surgicel from tissue implantation sites is presented.
先前的报告表明，局部止血剂 Surgicel 会从植入部位被吸收。在早期的一项研究中，已表明该材料由糖醛酸成分和纤维残渣组成。研究证明了在植入后18小时内糖醛酸成分会出现化学定量损失。本研究的目的是利用光学显微镜和电子显微镜检查大鼠组织中纤维残渣的去向。结果表明，这种纤维成分在植入部位被巨噬细胞吞噬。本文提出了一个 Surgicel 从组织植入部位清除的模型。
