Nappi J F, Lehman J A
Cleft Palate J. 1980 Oct;17(4):291-6.
The subperiosteal implantation of Surgicel has been advocated for the stimulation of bone formation by some authors. A clinical trial in five patients demonstrated no radiographic evidence of bone formation after 12 months. An experimental model was designed in the rabbit. This study also demonstrated no radiographic or histologic evidence of bone formation with the use of subperiosteal Surgicel. The further use of Surgicel for the stimulation of bone formation is not recommended.
一些作者主张采用 Surgicel 骨膜下植入术来刺激骨形成。一项针对 5 名患者的临床试验表明，12 个月后影像学检查未发现骨形成迹象。在兔子身上设计了一个实验模型。该研究也表明，使用骨膜下 Surgicel 后，影像学和组织学检查均未发现骨形成迹象。不建议进一步使用 Surgicel 来刺激骨形成。
