De Paoli P, Battistin S, Reitano M, Crovatto M, Tirelli U, Diodato S, Santini G
J Clin Lab Immunol. 1987 Mar;22(3):117-9.
Combinations of monoclonal antibodies defining the OKT 4 positive lymphocyte subset in the peripheral blood of intravenous drug abusers suggest that the 4B4 positive helper inducer population is greatly reduced in subjects infected with HTLV III. No differences were seen instead using different antibodies directed against various epitopes of the T4 molecule. These results suggest that the multiple marker assay could be very useful to define immunological status during HTLV III infection in humans.
在静脉吸毒者外周血中定义OKT 4阳性淋巴细胞亚群的单克隆抗体组合表明，在感染HTLV III的受试者中，4B4阳性辅助诱导细胞群体大幅减少。相反，使用针对T4分子不同表位的不同抗体时未观察到差异。这些结果表明，多重标记检测对于确定人类HTLV III感染期间的免疫状态可能非常有用。
