Cho Min Jeong, Choi Youn Hee, Kim Hyeon Chang, Shim Jee Seon, Amano Atsuo, Kim Ji Young, Song Keun Bae
Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea.
Institute for Translational Research in Dentistry, Kyungpook National University, Daegu, Korea.
Yonsei Med J. 2019 Jun;60(6):554-560. doi: 10.3349/ymj.2019.60.6.554.
In general, the prevalence of metabolic syndrome (MS) and tooth loss increases with age. We investigated the relationship between the presence of MS, its elements, and tooth loss in middle-aged Korean adults.
This study included Korean adults between 30 and 64 years of age who resided in the capital area of Seoul. From January to June 2014, individuals interested in participating in the oral health survey among those who visited the university hospital's cardiovascular center and provided informed consent were selected. Among 748 subjects who responded to the oral health questionnaires, 30 were excluded due to unclear responses; therefore, a total of 718 were included in the final analysis.
The crude odds ratio (OR) of ≥one MS component affecting tooth loss was 1.45 [95% confidence interval (CI), 1.06-2.00]. After adjusting for sex, age, education, income level, occupation, smoking status, kidney disease, chronic obstructive pulmonary disease, and rheumatic disease, the adjusted OR was 1.47 (95% CI, 1.06-2.05), which was statistically significant (<0.05). The OR for tooth loss was higher in the presence of ≥one component of MS (50-64 years of age) in females.
This study suggests that female aged 50-64 years may have higher likelihood of tooth loss upon the presence of at least one MS component. Prevention against MS among female of older age could contribute to maintenance of remaining teeth. Further well-designed studies are needed.
一般而言，代谢综合征（MS）的患病率和牙齿缺失率会随着年龄的增长而增加。我们调查了韩国中年成年人中MS的存在及其各要素与牙齿缺失之间的关系。
本研究纳入了居住在首尔首都地区、年龄在30至64岁之间的韩国成年人。2014年1月至6月，从前往大学医院心血管中心并提供知情同意书的人群中，选取有兴趣参与口腔健康调查的个体。在748名回答了口腔健康问卷的受试者中，有30人因回答不明确而被排除；因此，最终分析共纳入718人。
至少一种MS组分影响牙齿缺失的粗比值比（OR）为1.45[95%置信区间（CI），1.06 - 2.00]。在对性别、年龄、教育程度、收入水平、职业、吸烟状况、肾脏疾病、慢性阻塞性肺疾病和风湿性疾病进行校正后，校正后的OR为1.47（95%CI，1.06 - 2.05），具有统计学意义（<0.05）。在女性中，年龄在50 - 64岁且存在至少一种MS组分时，牙齿缺失的OR更高。
本研究表明，50 - 64岁的女性在存在至少一种MS组分时，牙齿缺失的可能性可能更高。预防老年女性的MS可能有助于保留剩余牙齿。需要进一步设计良好的研究。
