Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Department of Pediatrics, Division of Neonatology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Ophthalmol. 2019 Jun;67(6):866-870. doi: 10.4103/ijo.IJO_1608_18.
To compare the outcomes of conventional laser photocoagulation versus additional posterior barrage laser in advanced stage 3 retinopathy of prematurity (ROP).
A total of 20 infants with bilateral symmetric zone 2 stage 3 advancing ROP were treated with conventional laser treatment followed by randomization of one eye to receive additional posterior retinal laser treatment. Disc-fovea and inter-arcade distance was measured. The patients were followed up prospectively for 3 months. Structural and functional outcomes and safety profile were analyzed.
18/20 (90%) eyes in the study group and 19/20 (95%) eyes in the control group achieved regression of disease. Faster and complete regression was observed at 4 weeks after posterior laser compared to the control group (P = 0.024). Disc-fovea and inter-arcade distance was comparable in both groups.
Additional posterior barrage laser is a safe technique that led to faster and more complete regression in eyes with advancing ROP. Final regression profile was comparable in both treatment modalities.
比较传统激光光凝与晚期 3 期早产儿视网膜病变（ROP）后巩膜激光光凝的疗效。
对 20 例双侧对称性 2 区 3 期进展性 ROP 的婴儿进行常规激光治疗，然后随机对一只眼进行后巩膜激光治疗。测量视盘-黄斑和血管弓间的距离。前瞻性随访 3 个月，分析结构和功能结局及安全性。
研究组 20 只眼（90%）和对照组 20 只眼（95%）均有疾病消退。与对照组相比，后巩膜激光治疗后 4 周时，疾病消退更快、更完全（P = 0.024）。两组视盘-黄斑和血管弓间的距离均无差异。
后巩膜激光光凝是一种安全的技术，可使进展性 ROP 眼更快、更完全地消退。两种治疗方式的最终消退情况相似。
