Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
Arch Iran Med. 2019 Apr 1;22(4):213-216.
Solid pseudopapillary tumor of pancreas (SPTP) is a rare tumor of the pancreas which mostly occurs in young women. Since its first description in 1969, more than 500 cases have been reported. There have been just 2 case reports and 1 review (7 cases) from Iran. In this study, we reported our experience with 22 patients with SPT from the largest pancreaticobiliary center in Southern Iran.
During 6 years (2012-2017), 22 cases of SPTP were operated on in our center. All of these cases were recruited and after confirmation of the pathological diagnosis, clinical charts were evaluated and all the clinicopathologic findings as well as outcome of the surgery were evaluated.
Among the 22 patients, 20 were female and 2 were males. The age range was 15-52 years and the tumor sizes were 3.5 to 17 cm. All of the tumors had preoperative diagnosis by imaging modalities and were operated on with no complication or recurrences. Just one case showed liver metastasis. All of the patients with SPTP in this study were alive and in good condition.
SPTP is not very rare in our center. In young patients presenting with pancreatic mass, especially in female patients, one of the most important diagnoses is SPTP. Conservative surgery and tumor excision is satisfactory and patients show excellent prognosis even after liver metastasis.
胰腺实性假乳头状瘤(SPTP)是一种罕见的胰腺肿瘤,主要发生在年轻女性中。自 1969 年首次描述以来,已经报告了超过 500 例病例。来自伊朗的病例报告仅有 2 例和 1 篇综述(7 例)。在本研究中,我们报告了来自伊朗南部最大的胰腺胆道中心的 22 例 SPT 患者的经验。
在 6 年(2012-2017 年)期间,我们中心对 22 例 SPTP 患者进行了手术。所有这些病例均被招募,并在确认病理诊断后,评估了临床图表,并评估了所有临床病理发现以及手术结果。
在 22 例患者中,女性 20 例,男性 2 例。年龄范围为 15-52 岁,肿瘤大小为 3.5 至 17 厘米。所有肿瘤均通过影像学手段术前诊断,并进行了无并发症或复发的手术。仅有 1 例病例显示肝转移。本研究中所有 SPTP 患者均存活且状况良好。
在我们中心,SPTP 并不罕见。在年轻患者出现胰腺肿块时,特别是女性患者,最重要的诊断之一是 SPTP。保守手术和肿瘤切除是令人满意的,即使发生肝转移,患者也表现出极好的预后。