Department of Cardiology, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins Medical Institutions, Baltimore, MD, USA; School of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat Del Vallès, Barcelona, Spain.
Department of Epidemiology, Azienda Zero, Veneto Region, Italy.
Atherosclerosis. 2019 Jul;286:105-113. doi: 10.1016/j.atherosclerosis.2019.05.014. Epub 2019 May 16.
South Asian (SA) individuals represent a large, growing population in a number of European countries. These individuals, particularly first-generation SA immigrants, are at higher risk of developing type 2 diabetes, atherogenic dyslipidaemia, and coronary heart disease than most other racial/ethnic groups living in Europe. SAs also have an increased risk of stroke compared to European-born individuals. Despite a large body of conclusive evidence, SA-specific cardiovascular health promotion and preventive interventions are currently scarce in most European countries, as well as at the European Union level. In this narrative review, we aim to increase awareness among clinicians and healthcare authorities of the public health importance of cardiovascular disease among SAs living in Europe, as well as the need for tailored interventions targeting this group - particularly, in countries where SA immigration is a recent phenomenon. To this purpose, we review key studies on the epidemiology and risk factors of cardiovascular disease in SAs living in the United Kingdom, Italy, Spain, Denmark, Norway, Sweden, and other European countries. Building on these, we discuss potential opportunities for multi-level, targeted, tailored cardiovascular prevention strategies. Because lifestyle interventions often face important cultural barriers in SAs, particularly for first-generation immigrants; we also discuss features that may help maximise the effectiveness of those interventions. Finally, we evaluate knowledge gaps, currently available risk stratification tools such as QRISK-3, and future directions in this important field.
南亚(SA)个体在许多欧洲国家代表着一个庞大且不断增长的人群。这些个体,尤其是第一代 SA 移民,比生活在欧洲的大多数其他种族/族裔群体更容易患 2 型糖尿病、致动脉粥样硬化血脂异常和冠心病。与欧洲出生的个体相比,SA 也有更高的中风风险。尽管有大量确凿的证据,但在大多数欧洲国家以及欧盟层面,针对 SA 的心血管健康促进和预防干预措施目前仍然很少。在这篇叙述性评论中,我们旨在提高临床医生和医疗保健当局对欧洲生活的 SA 人群中心血管疾病的公共卫生重要性的认识,以及针对这一群体的量身定制干预措施的必要性——特别是在 SA 移民是最近才出现的国家。为此,我们回顾了关于生活在英国、意大利、西班牙、丹麦、挪威、瑞典和其他欧洲国家的 SA 人群中心血管疾病的流行病学和危险因素的关键研究。在此基础上,我们讨论了多层次、有针对性、量身定制的心血管预防策略的潜在机会。由于生活方式干预在 SA 中经常面临重要的文化障碍,特别是对于第一代移民;我们还讨论了可能有助于最大限度地提高这些干预措施有效性的特征。最后,我们评估了这一重要领域的知识差距、目前可用的风险分层工具(如 QRISK-3)以及未来的方向。