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预测剖宫产术后阴道分娩的成功率:中国的一项回顾性队列研究。

Predicting the success of vaginal birth after caesarean delivery: a retrospective cohort study in China.

机构信息

Shenzhen Longhua District Central Hospital, Shenzhen, P.R. China.

Dongguan Tangxia Hospital, Dongguan, P.R. China.

出版信息

BMJ Open. 2019 May 24;9(5):e027807. doi: 10.1136/bmjopen-2018-027807.

Abstract

OBJECTIVES

To develop a nomogram to predict the likelihood of vaginal birth after caesarean section (VBAC) among women after a previous caesarean section (CS).

DESIGN

A retrospective cohort study.

SETTING

Two secondary hospitals in Guangdong Province, China.

PARTICIPANTS

Inclusion criteria were as follows: pregnant women with singleton fetus, age ≥18 years, had a history of previous CS and scheduled for trial of labour after caesarean delivery (TOLAC). Patients with any of the following were excluded from the study: preterm labour (gestational age <37 weeks), two or more CSs, contradictions for vaginal birth, history of other uterine incision such as myomectomy, and incomplete medical records.

PRIMARY OUTCOME MEASURE

The primary outcome was VBAC, which was retrospectively abstracted from computerised medical records by clinical staff.

RESULTS

Of the women who planned for TOLAC, 84.0% (1686/2006) had VBAC. Gestational age, history of vaginal delivery, estimated birth weight, body mass index, spontaneous onset of labour, cervix Bishop score and rupture of membranes were independently associated with VBAC. An area under the receiver operating characteristic curve (AUC) in the prediction model was 0.77 (95% CI 0.73 to 0.81) in the training cohort. The validation set showed good discrimination with an AUC of 0.70 (95% CI 0.60 to 0.79).

CONCLUSIONS

TOLAC may be a potential strategy for decreasing the CS rate in China. The validated nomogram to predict success of VBAC could be a potential tool for VBAC counselling.

摘要

目的

开发一种列线图,以预测既往剖宫产(CS)后妇女 CS 后阴道分娩(VBAC)的可能性。

设计

回顾性队列研究。

地点

中国广东省的两家二级医院。

参与者

纳入标准如下:单胎妊娠、年龄≥18 岁、有既往 CS 史且计划行 CS 后试产(TOLAC)的孕妇。有以下任何一种情况的患者将被排除在研究之外:早产(孕周<37 周)、两次或以上 CS、阴道分娩禁忌证、既往有其他子宫切口史(如子宫肌瘤切除术)和病历不完整。

主要结局指标

主要结局是 VBAC,由临床工作人员从计算机化的病历中回顾性提取。

结果

在计划行 TOLAC 的孕妇中,84.0%(1686/2006)实现了 VBAC。孕周、阴道分娩史、估计出生体重、体重指数、自发临产、宫颈 Bishop 评分和胎膜破裂与 VBAC 独立相关。预测模型在训练队列中的受试者工作特征曲线下面积(AUC)为 0.77(95%CI 0.73 至 0.81)。验证集显示出良好的判别能力,AUC 为 0.70(95%CI 0.60 至 0.79)。

结论

TOLAC 可能是降低中国 CS 率的一种潜在策略。验证的 VBAC 成功预测列线图可以成为 VBAC 咨询的潜在工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bd4/6538023/ce2693326e8a/bmjopen-2018-027807f01.jpg

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