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抗阻训练和联合训练对2型糖尿病血管功能的影响:随机对照试验的系统评价

Effects of Resistance and Combined training on Vascular Function in Type 2 Diabetes: A Systematic Review of Randomized Controlled Trials.

作者信息

Dos Santos Araujo João E, Nunes Macedo Fabrício, Sales Barreto André, Viana Dos Santos Márcio R, Antoniolli Angelo R, Quintans-Junior Lucindo J

机构信息

Laboratory of Cardiovascular Pharmacology, Department of Physiology, Federal University of Sergipe, Sergipe, Brazil.

Laboratory of Neurosciences and Pharmacological Trials, Department of Physiology, Federal University of Sergipe, Sergipe, Brazi.

出版信息

Rev Diabet Stud. 2019;15:16-25. doi: 10.1900/RDS.2019.15.16. Epub 2019 Apr 19.

Abstract

BACKGROUND

Cardiovascular disease (CVD) is the main cause of mortality in type 2 diabetes (T2D). Exercise can reduce the risk factors associated with CVD in T2D patients. However, research evaluating its beneficial effects in these patients has used different measurement protocols and types of exercise, complicating comparison.

AIM

To assess the effects of resistance training (RT) and combined training (CT) on the vascular function of T2D patients.

METHODS

A database search (MEDLINE, Scopus, and Web of Science) was performed to identify relevant articles that were published up to August 2017. Only original studies evaluating the effects of RT or CT interventions on vascular function in T2D patients were included. The articles were reviewed independently by at least three reviewers. The Cochrane guidelines were used to assess the methodological quality of the studies. Fourteen studies were finally included. Two studies only used RT and twelve studies used CT as intervention strategy.

RESULTS AND CONCLUSIONS

The results show that resistance training is a useful means for primary treatment of vascular diseases and maintenance of vascular function in T2D patients. However, more studies are necessary to gain full knowledge of the beneficial effects and to identify tailored exercise plans to optimize these benefits. The information provided in this review may help to improve current treatment of vascular diseases in T2D patients and to design future studies.

摘要

背景

心血管疾病(CVD)是2型糖尿病(T2D)患者死亡的主要原因。运动可以降低T2D患者中与CVD相关的危险因素。然而,评估运动对这些患者有益效果的研究采用了不同的测量方案和运动类型,这使得比较变得复杂。

目的

评估抗阻训练(RT)和联合训练(CT)对T2D患者血管功能的影响。

方法

进行数据库检索(MEDLINE、Scopus和科学网),以识别截至2017年8月发表的相关文章。仅纳入评估RT或CT干预对T2D患者血管功能影响的原始研究。文章由至少三名评审员独立评审。采用Cochrane指南评估研究的方法学质量。最终纳入14项研究。两项研究仅使用RT,12项研究使用CT作为干预策略。

结果与结论

结果表明,抗阻训练是T2D患者血管疾病初级治疗和维持血管功能的有效手段。然而,需要更多研究来全面了解其有益效果,并确定量身定制的运动计划以优化这些益处。本综述提供的信息可能有助于改善T2D患者当前的血管疾病治疗,并设计未来的研究。

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