University of California San Francisco, Urology, San Francisco, CA.
King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Urology. 2019 Sep;131:57-63. doi: 10.1016/j.urology.2019.05.009. Epub 2019 May 25.
To determine social factors associated with advanced stone disease (defined as unilateral stone burden >2 cm) at time of presentation to a regional stone referral center. Little is known about social determinants of urolithiasis. We hypothesize that socioeconomic factors impact kidney stone severity at intake to referral centers.
A retrospective review of the prospectively collected data from the Registry for Stones of the Kidney and Ureter from 2015 to 2018 was conducted to evaluate patient characteristics predictive of having a large (>2 cm) unilateral kidney stone. Data on patient age, gender, body mass index, diabetes, race, language, education level, infection, distance, income, referring regional urologist density, American Society of Anesthesiologists score, and stone analysis were evaluated.
Complete imaging and patient variable data was present in 650 of 1142 patients including 197 patients with unilateral stone burden >2 cm. On multivariate analysis, obesity, lower education level, increased distance from the referral center, and symptoms of infection predicted for unilateral stone burden greater than 2 cm. Among 191 patients with stone analysis data present, stone type, income, and urologist density predicted for unilateral stone burden greater than 2 cm.
In addition to known biological risk factors, patients with lower education levels and from regions of lower mean income were found to be more likely to present to our tertiary care center with stone burden greater than 2 cm. More research is needed to elucidate the social and societal determinants of advanced stone disease and the impact this has on population costs for stone treatment.
确定在向区域结石转诊中心就诊时与晚期结石病(定义为单侧结石负担>2cm)相关的社会因素。人们对尿石症的社会决定因素知之甚少。我们假设社会经济因素会影响到结石进入转诊中心时的严重程度。
对 2015 年至 2018 年期间前瞻性收集的肾脏和输尿管结石登记处的数据进行回顾性分析,以评估预测存在大(>2cm)单侧肾结石的患者特征。评估患者的年龄、性别、体重指数、糖尿病、种族、语言、教育水平、感染、距离、收入、转诊区域泌尿科医生密度、美国麻醉师协会评分和结石分析等数据。
在 1142 名患者中,有 650 名患者包括 197 名单侧结石负担>2cm 的患者,其中包括完整的影像学和患者变量数据。在多变量分析中,肥胖、教育水平较低、与转诊中心的距离增加以及感染症状预测单侧结石负担>2cm。在 191 名有结石分析数据的患者中,结石类型、收入和泌尿科医生密度预测单侧结石负担>2cm。
除了已知的生物学危险因素外,教育水平较低和收入较低地区的患者更有可能因结石负担>2cm 而到我们的三级护理中心就诊。需要进一步研究阐明晚期结石病的社会和社会决定因素,以及这对结石治疗的人群成本的影响。