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使用无缝合Perceval瓣膜治疗瓷化主动脉严重主动脉瓣反流的新方法:一例报告。

A new approach for severe aortic regurgitation in porcelain aorta with sutureless Perceval valve: A case report.

作者信息

Martinelli Gian Luca, Cotroneo Attilio, Stelian Edmond, Benea Diana, Diena Marco

机构信息

CardioVascular Dept., Clinica San Gaudenzio - Gruppo Policlinico di Monza, 3, Via Bottini, Novara, 28100, Italy.

CardioVascular Dept., Clinica San Gaudenzio - Gruppo Policlinico di Monza, 3, Via Bottini, Novara, 28100, Italy.

出版信息

Int J Surg Case Rep. 2019;59:124-127. doi: 10.1016/j.ijscr.2019.04.044. Epub 2019 May 13.

DOI:10.1016/j.ijscr.2019.04.044
PMID:31132610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6536741/
Abstract

INTRODUCTION

The association of pure aortic regurgitation and porcelain aorta represents a challenging situation. In the Transcatheter Aortic Valve Implantation (TAVI) era, porcelain aorta (PA) becomes an additional risk for patient treatment and sometimes serves as the primary indication for the TAVI approach, even in low-risk patients. Devices currently on the market are not yet validated for the treatment of pure aortic regurgitation (AR) in PA and mid/long-term results are still not available. Furthermore, small calcified sinotubular junction and the association of small Valsalva sinus with low origin of coronaries ostia represent a relative contraindication of TAVI.

PRESENTATION OF CASE

We report a case of severe symptomatic AR associated with a PA in a patient successfully treated with a sutureless Perceval valve.

DISCUSSION

The sutureless Perceval valve may represent an excellent option. This valve requires less manipulation of the ascending aorta and no manipulation of the aortic annulus except for the aortic valve leaflets removal. Furthermore, it can be implanted also in a small and calcified sino-tubular junction because the valve is collapsible before the implant.

CONCLUSION

The present case represents a proof that self-expandable cardiac valve technology can be employed to treat, either by surgery or by catheter, selected cases of AR. We have observed an excellent mid term result with no paravalvular leak at 2 years.

摘要

引言

单纯主动脉瓣反流与瓷化主动脉的关联是一种具有挑战性的情况。在经导管主动脉瓣植入术(TAVI)时代,瓷化主动脉(PA)成为患者治疗的额外风险,有时甚至是TAVI治疗方法的主要指征,即使在低风险患者中也是如此。目前市场上的器械尚未经过验证用于治疗PA中的单纯主动脉瓣反流(AR),且中期和长期结果仍不可得。此外,小钙化的窦管交界处以及小瓦氏窦与冠状动脉开口低位的关联是TAVI的相对禁忌证。

病例介绍

我们报告一例严重症状性AR合并PA的患者,成功接受了无缝合Perceval瓣膜治疗。

讨论

无缝合Perceval瓣膜可能是一个极佳的选择。该瓣膜对升主动脉的操作要求较低,除了切除主动脉瓣叶外,无需对主动脉瓣环进行操作。此外,它还可植入小且钙化的窦管交界处,因为该瓣膜在植入前可折叠。

结论

本病例证明可采用自膨胀心脏瓣膜技术,通过手术或导管治疗特定的AR病例。我们观察到中期结果极佳,2年时无瓣周漏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/febc2696d6c4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/5b9cd2cce7fd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/3521e7f6e31c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/febc2696d6c4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/5b9cd2cce7fd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/3521e7f6e31c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7b/6536741/febc2696d6c4/gr3.jpg

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本文引用的文献

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Five-year results of the pilot trial of a sutureless valve.无缝线瓣膜的初步试验的 5 年结果。
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Aortic valve replacement with the perceval S bioprosthesis: single-center experience in 143 patients.
使用Perceval S生物瓣膜进行主动脉瓣置换术:143例患者的单中心经验。
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The safety of deep hypothermic circulatory arrest in aortic valve replacement with unclampable aorta in non-octogenarians.非八旬老人中主动脉不可夹闭的主动脉瓣置换术采用深低温停循环的安全性
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Not all porcelain is the same: classification of circular aortic calcifications (porcelain aorta) according to the impact on therapeutic approach.并非所有的瓷化都相同:根据对治疗方法的影响对圆形主动脉钙化(瓷化主动脉)进行分类。
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