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阳极经颅直流电刺激作用于运动皮层与小脑对脑瘫影响的研究方案

Effect of Anodic tDCS Over Motor Cortex Versus Cerebellum in Cerebral Palsy: A Study Protocol.

作者信息

Villalta Santos Lucas, Benite Palma Lopes Jamile, Almeida Carvalho Duarte Natália, Galli Manuela, Collange Grecco Luanda André, Santos Oliveira Claudia

机构信息

Health Sciences (Mr Santos, Ms Lopes, and Drs Duarte and Oliveira), Santa Casa de São Paulo School of Medical Sciences, São Paulo, SP, Brazil; Vento Leste-Specialized Childcare Habilitation (Mr Santos and Dr Grecco), Sorocaba, SP, Brazil; Department of Electronic Information and Bioengineering (Dr Galli), Politecnico di Milano, Milan, Italy; Laboratory of Integrated Human Movements (Dr Grecco), Universidade de Sorocaba, Sorocaba, SP, Brazil; Center of Pediatric Neurostimulation (Dr Grecco), São Paulo, SP, Brazil; University Center of Anápolis (Dr Oliveira), Anápolis, GO, Brazil.

出版信息

Pediatr Phys Ther. 2019 Jul;31(3):301-305. doi: 10.1097/PEP.0000000000000626.

DOI:10.1097/PEP.0000000000000626
PMID:31135599
Abstract

PURPOSE

To compare the clinical and functional effects of treadmill training combined with anodic transcranial direct current stimulation (atDCS) on the primary motor cortex (Cz), specifically on the area of motor cortex representation of the lower limbs, and on the cerebellum (Cb) in children with spastic cerebral palsy (CP).

METHODS

Thirty children and adolescents with spastic CP will be randomly allocated in 3 groups: (1) treadmill training and atDCS on Cz; (2) treadmill training and atDCS on Cb; (3) treadmill training and sham tDCS on Cz. Evaluations of gait spatial-temporal parameters, functional mobility, functional balance, gross motor function, and functional performance will be performed 1 week before intervention and 1 week, 1 month, and 3 months after intervention. Every 3 months the participants will cross over groups.

DISCUSSION

This is a protocol for an intervention study comparing the clinical and functional effects of atDCS over Cz and Cb.

摘要

目的

比较跑步机训练结合阳极经颅直流电刺激(atDCS)对痉挛型脑瘫(CP)患儿初级运动皮层(Cz),特别是下肢运动皮层代表区,以及小脑(Cb)的临床和功能影响。

方法

30名痉挛型CP儿童和青少年将被随机分为3组:(1)在Cz进行跑步机训练和atDCS;(2)在Cb进行跑步机训练和atDCS;(3)在Cz进行跑步机训练和假tDCS。将在干预前1周以及干预后1周、1个月和3个月进行步态时空参数、功能移动性、功能平衡、粗大运动功能和功能表现的评估。每3个月参与者将进行组间交叉。

讨论

这是一项干预研究方案,比较atDCS对Cz和Cb的临床和功能影响。

相似文献

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Effect of Anodic tDCS Over Motor Cortex Versus Cerebellum in Cerebral Palsy: A Study Protocol.阳极经颅直流电刺激作用于运动皮层与小脑对脑瘫影响的研究方案
Pediatr Phys Ther. 2019 Jul;31(3):301-305. doi: 10.1097/PEP.0000000000000626.
2
Effect of transcranial direct-current stimulation combined with treadmill training on balance and functional performance in children with cerebral palsy: a double-blind randomized controlled trial.经颅直流电刺激联合跑步机训练对脑瘫患儿平衡能力和功能表现的影响:一项双盲随机对照试验
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引用本文的文献

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Safety and effectiveness of non-invasive brain stimulation on mobility and balance function in children with cerebral palsy: a systematic review and meta-analysis.非侵入性脑刺激对脑瘫患儿运动和平衡功能的安全性与有效性:一项系统评价和荟萃分析
J Neuroeng Rehabil. 2025 May 18;22(1):111. doi: 10.1186/s12984-025-01619-7.
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New Perspectives on Non-Invasive Cerebellar Stimulation for Social and Affective Functions in Children and Adolescents.儿童和青少年社交与情感功能的无创小脑刺激新视角
Cerebellum. 2025 Apr 26;24(4):88. doi: 10.1007/s12311-025-01844-9.
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Standardized Outcomes Measures in Physical Therapy Practice for Treatment and Rehabilitation of Cerebral PALSY: A Systematic Review.
物理治疗实践中用于脑瘫治疗和康复的标准化结局测量:一项系统综述。
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