Koster Markus, Ritter Simon, Brändle Michael
1 Klinik für Allgemeine Innere Medizin/Hausarztmedizin, Departement Innere Medizin, Kantonsspital St. Gallen.
2 Klinik für Innere Medizin, Spital Herisau, Spitalverbund Appenzell Ausserrhoden.
Praxis (Bern 1994). 2019;108(7):495-498. doi: 10.1024/1661-8157/a003234.
Rapid Resolution of Symptomatic Hypercalcaemia Milk-alkali syndrome consists of the triad of hypercalcaemia, metabolic alkalosis, and renal insufficiency associated with the ingestion of calcium and absorbable alkali. Older patients, those at risk for volume depletion and those on medications that reduce glomerular filtration rate are at increased risk for the development of this syndrome. Most affected patients are postmenopausal women with chronic kidney disease who take an excessive amount of calcium carbonate. The incidence of milk-alkali syndrome is increasing due to the common supplementation of calcium carbonate. Nowadays, it is the third most common cause of hypercalcaemia. As shown in this case, hypercalcaemia may occur even with small amounts of calcium carbonate in patients with the given risk factors.
症状性高钙血症的快速缓解 乳碱综合征由高钙血症、代谢性碱中毒和肾功能不全三联征组成，与摄入钙和可吸收碱有关。老年患者、有容量耗竭风险的患者以及服用降低肾小球滤过率药物的患者发生该综合征的风险增加。大多数受影响的患者是患有慢性肾病的绝经后女性，她们摄入了过量的碳酸钙。由于碳酸钙的普遍补充，乳碱综合征的发病率正在上升。如今，它是高钙血症的第三大常见病因。如此病例所示，在有特定风险因素的患者中，即使摄入少量碳酸钙也可能发生高钙血症。
