Associate Consultant, Department of Medicine, Pentamed Hospital, Delhi, India, Corresponding Author.
Associate Consultant, Department of Medicine, Pentamed Hospital, Delhi, India.
J Assoc Physicians India. 2023 Sep;71(9):104-105. doi: 10.59556/japi.71.0330.
The Milk-Alkali syndrome (MAS) is identified by the triad of high serum levels of calcium, metabolic alkalosis, and acute kidney injury, usually caused by consuming excessive amounts of calcium and absorbable alkali. If not treated promptly, the syndrome can result in rapid hypercalcemia, acute renal failure, and metastatic calcification. Notably, an increasing number of cases of MAS have been observed, potentially due to the rampant use of calcium-based over-the-counter supplements for the prevention and treatment of osteoporosis in postmenopausal women. Herein, we report a case of severe hypercalcemia due to prolonged intake of calcium carbonate supplements in the absence of any alkali. The case report highlights the importance of including venous blood gas (VBG) analysis as a part of the workup for hypercalcemia, as metabolic alkalosis can help clinch the diagnosis of MAS in the setting of severe hypercalcemia. How to cite this article: Sahu U, Trivedi T, Gupta R. Milk-Alkali Syndrome: A Century-old Cause of Hypercalcemia Requires the Addition of Venous Blood Gas in Hypercalcemia Workup. J Assoc Physicians India 2023;71(9):104-105.
乳碱综合征（MAS）的特征为血清钙水平升高、代谢性碱中毒和急性肾损伤三联征，通常由摄入过多的钙和可吸收的碱引起。如果不及时治疗，该综合征可导致血钙迅速升高、急性肾衰竭和转移性钙化。值得注意的是，由于绝经后妇女广泛使用钙补充剂来预防和治疗骨质疏松症，观察到越来越多的 MAS 病例，潜在地导致了 MAS 的发生。在此，我们报告了一例因长期摄入碳酸钙补充剂而导致严重高钙血症的病例，且无任何碱摄入。该病例报告强调了在高钙血症的检查中包括静脉血气（VBG）分析的重要性，因为在严重高钙血症的情况下，代谢性碱中毒有助于确诊 MAS。如何引用本文：Sahu U, Trivedi T, Gupta R. 乳碱综合征：一个百年的高钙血症病因，在高钙血症检查中需要增加静脉血气。J 印度医师协会 2023;71(9):104-105.
