School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Molecules. 2019 May 20;24(10):1944. doi: 10.3390/molecules24101944.
Red yeast rice (RYR) is made by fermenting the rice with . It is commonly used in food colorants, dyeing, and wine making in China and its neighboring countries. Nowadays RYR has two forms on the market: common RYR is used for food products, the other form is functional RYR for medicine. However, some researchers reported that commercial lovastatin (structure is consistent with monacolin K) is illegally added to common RYR to meet drug quality standards, so as to imitate functional RYR and sell the imitation at a higher price. Based on current detection methods, it is impossible to accurately distinguish whether functional RYR is adulterated. Therefore, it is especially important to find a way to authenticate functional RYR. In the current review, the advances in history, applications, components (especially monacolins, monacolins detection methods), quality standards, authentication methods and perspectives for the future study of RYR are systematically reviewed.
红曲米(RYR)是通过将大米与. 发酵制成的。它在中国及其邻国被广泛用于食品着色剂、染料和酿酒。如今,RYR 在市场上有两种形式:普通 RYR 用于食品产品,另一种形式是功能性 RYR 用于药品。然而,一些研究人员报告说,商业洛伐他汀(结构与莫纳可林 K 一致)被非法添加到普通 RYR 中,以满足药品质量标准,从而模仿功能性 RYR 并以更高的价格销售仿制品。基于当前的检测方法,无法准确区分功能性 RYR 是否被掺假。因此,找到一种鉴定功能性 RYR 的方法尤为重要。在目前的综述中,系统地回顾了 RYR 的历史、应用、成分(特别是莫纳可林、莫纳可林检测方法)、质量标准、鉴定方法和未来研究的展望。