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创伤后应激障碍(PTSD):异常侵入性胎盘(AIP)的心理后遗症。

Post traumatic stress disorder (PTSD): The psychological sequelae of abnormally invasive placenta (AIP).

机构信息

The Medical Sciences Division, University of Oxford, Oxford, UK.

Department of Psychological Medicine, Oxford University Hospitals, Oxford, UK.

出版信息

Placenta. 2019 Jun;81:42-45. doi: 10.1016/j.placenta.2019.04.004. Epub 2019 Apr 16.

Abstract

INTRODUCTION

Abnormally invasive placenta (AIP) is a rare pregnancy complication often resulting in postpartum haemorrhage (PPH) and emergency peripartum hysterectomy (EPH). The risk of developing post traumatic stress disorder (PTSD) following unexpectedly traumatic childbirth is known however there is no evidence regarding PTSD in AIP. This pilot study assesses the risk of PTSD for women with AIP compared to women having an uncomplicated caesarean delivery (CD) or unexpected PPH or EPH.

METHODS

Retrospective case-controlled questionnaire study in a UK Tertiary obstetric unit. Women with AIP (Group-1) were matched by delivery date to control groups: Group-2, women with an uncomplicated CD; Group-3 women referred to a specialist clinic for suspected AIP, but had a normal placenta and uncomplicated CD; Group-4, women who had an unexpected EPH and/or severe (>3000 mls) PPH. 218 women were sent a validated PTSD screening questionnaire (Impacts of Events Scale-Revised [IES-R]).

RESULTS

Likelihood of PTSD was recorded for 69 women who responded, revealing significantly higher PTSD scores for women with AIP compared to uncomplicated CD (P = 0.001). No significant difference was seen between AIP and EPH/PPH (P = 0.89). The number of women with scores high enough to indicate probable PTSD was significantly greater with AIP than uncomplicated CD group (P = 0.045).

DISCUSSION

This study demonstrates that women antenatally diagnosed with AIP and anticipating a potentially traumatic delivery, are at significantly increased risk of developing PTSD. Improved awareness of the negative psychological impact of AIP may increase the number of women being identified and treated, thereby improving their quality of life.

摘要

简介

异常侵袭性胎盘(AIP)是一种罕见的妊娠并发症,常导致产后出血(PPH)和紧急剖宫产时子宫切除术(EPH)。已知意外创伤性分娩后发生创伤后应激障碍(PTSD)的风险,但尚无关于 AIP 后 PTSD 的证据。这项初步研究评估了与患有简单剖宫产(CD)或意外 PPH 或 EPH 的女性相比,患有 AIP 的女性发生 PTSD 的风险。

方法

在英国一家三级产科单位进行回顾性病例对照问卷调查研究。AIP 女性(第 1 组)按分娩日期与对照组匹配:第 2 组为接受简单 CD 的女性;第 3 组为因疑似 AIP 而转至专科诊所的女性,但胎盘正常且 CD 简单;第 4 组为发生意外 EPH 和/或大量(>3000 毫升)PPH 的女性。218 名女性收到了一份经过验证的 PTSD 筛查问卷(修订后的事件影响量表 [IES-R])。

结果

记录了 69 名回复问卷的女性 PTSD 的可能性,结果显示 AIP 女性的 PTSD 评分明显高于简单 CD 组(P=0.001)。AIP 与 EPH/PPH 之间未见显著差异(P=0.89)。AIP 组得分高到表明可能患有 PTSD 的女性人数明显多于简单 CD 组(P=0.045)。

讨论

本研究表明,产前诊断为 AIP 并预计分娩过程可能会受到创伤的女性,发生 PTSD 的风险显著增加。提高对 AIP 对心理负面影响的认识,可能会增加识别和治疗的女性人数,从而提高她们的生活质量。

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