State Key Laboratory of Bioelectronics, National Demonstration Center for Experimental Biomedical Engineering Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Mikrochim Acta. 2019 May 28;186(6):384. doi: 10.1007/s00604-019-3444-3.
We report on the synthesis of chromium(III)-doped carbon dots (Cr-CDs) by one-pot hydrothermal pathway using tris(2, 4-pentanedionato) chromium(III) and polyethyleneimine as precursors. The Cr-CDs have a graphene-analogous structure and display blue-green fluorescence with excitation/emission maxima at 350/466 nm, a 20% quantum yield, and excitation-independent emissions. Their cytotoxicity is low. The Cr-CDs were used as a fluorescence probe for p-nitrophenol (p-NP). The assay has a linear working range that extends from 0.8~150 μM and a 0.27 μM lower detection limit. The assay was applied to the detecting of p-NP in spiked human urine, and conceivably may be extended to a method for the determination of parathion. Graphical abstract Schematic presentation for the synthesis of Cr-CDs (chromium(III)-doped carbon dots) and their application to the fluorometric determination of p-NP (p-nitrophenol) based on an inner filter effect.
我们报告了一种通过一步水热途径合成掺铬碳点（Cr-CDs）的方法，该方法以三（2,4-戊二酮）铬（III）和聚乙烯亚胺为前体。Cr-CDs 具有类石墨烯结构，在 350/466nm 处显示出蓝绿色荧光，量子产率为 20%，且发射光不依赖于激发光。其细胞毒性较低。Cr-CDs 可用作对硝基苯酚（p-NP）的荧光探针。该分析方法的线性工作范围从 0.8μM 到 150μM，检测限低至 0.27μM。该方法已应用于加标人尿中 p-NP 的检测，推测可能扩展到测定对硫磷的方法。
