Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry , Central China Normal University , Wuhan 430079 , P.R. China.
J Org Chem. 2019 Jun 21;84(12):8322-8329. doi: 10.1021/acs.joc.9b01160. Epub 2019 Jun 11.
An I/PhI(OAc) copromoted strategy using dimethyl sulfoxide as an "S/C2/O" source for preparing α-dicarbonylsulfoximine derivatives is reported. This process involves oxidative coupling to construct a C-N bond and electrophilic amination of dimethyl sulfoxide to afford an N═S bond, with dimethyl sulfoxide present in the final product as an intact molecule. Furthermore, tetramethylene sulfoxide as a solvent is also compatible with this amination reaction.
本文报道了一种使用 I/PhI(OAc) 共促进策略，以二甲亚砜作为“S/C2/O”源，制备α-二羰基磺酰亚胺衍生物的方法。该过程涉及氧化偶联构建 C-N 键和二甲亚砜的亲电氨化反应，形成 N═S 键，最终产物中二甲亚砜以完整分子的形式存在。此外，四亚甲基砜作为溶剂也与该氨化反应兼容。
