Faculty of Medicine, Department of Dermatology, Selcuk University, Selçuklu, Turkey.
Faculty of Medicine, Department of Radiology, Selcuk University, Selçuklu, Turkey.
Skin Res Technol. 2019 Nov;25(6):810-814. doi: 10.1111/srt.12725. Epub 2019 May 29.
Cicatricial alopecia (CA) is a group of disorder characterized by permanent destruction of the hair follicle. Shear wave elastography (SWE) and superb microvascular imaging (SMI) are noninvasive ultrasonic techniques which evaluate thickness, stiffness, and vascular index of tissues.
This study explored the ranges of cicatricial alopecia area and normal scalp with a combined modality of SMI and SWE and investigated the feasibility of their use in assessing these diseases.
Seventeen patients diagnosed with CA and twenty healthy controls were included in the study. SWE and SMI were performed with an Aplio 500 ultrasound system.
The mean age of patient group was 37.00 ± 13.16, and the mean age of the healthy controls were 36.00 ± 11.79. SWE results as m/s in cicatricial plaques ( = 5191) were higher than non-alopecic scalp areas ( = 4460) in patient group (t (16) = 2260; P = 0.038 < 0.05). SMI values in patient group (cicatricial plaques) ( = 1200) were significantly higher than control group SMI values ( = 0.005) (t (35) = 3.075; P = 0.012 < 0.05).
To the best of our knowledge, this is the first study to evaluate SWE and SMI scores in cicatricial alopecia. We found higher stiffness and vascularity in patient group. We conclude that SWE and SMI can show fibrosis and inflammation like previous studies. Especially, SWE as m/s is more sensitive than as kPa for cicatricial alopecia.
瘢痕性脱发（CA）是一组以毛囊永久性破坏为特征的疾病。剪切波弹性成像（SWE）和超微血流成像（SMI）是两种非侵入性超声技术，可评估组织的厚度、硬度和血管指数。
本研究旨在探讨 SMI 和 SWE 联合应用于评估 CA 患者头皮病变和正常头皮的范围，并探讨其在评估这些疾病中的可行性。
纳入 17 例 CA 患者和 20 例健康对照者，使用 Aplio 500 超声系统进行 SWE 和 SMI 检查。
患者组平均年龄为 37.00 ± 13.16 岁，健康对照组平均年龄为 36.00 ± 11.79 岁。患者组瘢痕斑块的 SWE 结果（m/s）为 5191，高于非脱发头皮区域的 SWE 结果（m/s）（4460）（t (16) = 2260；P = 0.038 < 0.05）。患者组瘢痕斑块的 SMI 值（m/s）（1200）明显高于对照组（0.005）（t (35) = 3.075；P = 0.012 < 0.05）。
据我们所知，这是首次评估 SWE 和 SMI 评分在瘢痕性脱发中的研究。我们发现患者组硬度和血管度更高。我们得出结论，SWE 和 SMI 可以像之前的研究一样显示纤维化和炎症。特别是，SWE 的 m/s 比 kPa 对瘢痕性脱发更敏感。
