Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China (mainland).
Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, and Blood Vessel Disease, Beijing, China (mainland).
Med Sci Monit. 2019 May 29;25:3998-4004. doi: 10.12659/MSM.916938.
BACKGROUND The aim of this study was to estimate the long-term efficacy of total aortic arch replacement combined with the frozen elephant trunk (TAR+FET) technique for aortic disease following a prior cardiac surgery procedure. MATERIAL AND METHODS We performed TAR+FET for 118 patients for major vessel disease following a prior cardiac procedure with median sternotomy incision. All patients were divided into 5 groups: in group A, the prior major procedure was aortic valve replacement (AVR); in group B, the prior major procedure was isolated ascending aorta replacement; in group C, the prior major procedure was aortic root replacement; in group D, the prior major procedure was aortic arch replacement or intervention; and in group E, the prior major procedure was 'other' cardiac operative procedure. The long-term follow-up visit results were estimated using the Kaplan-Meier method. RESULTS The 30-day mortality rate after the operation was 13.6% (16/118) - 2 died in group A, 1 in group B, 8 in group C, 4 in group D, and 1 in group E. Follow-up visits were completed in 99% of patients. The mean follow-up time was 47.6±36.3 months and 12 patients had died by follow-up, so the total long-term survival rate was 76.3%. One-year survival rates of the 5 groups were 85% (group A), 93.8% (group B), 82.3% (group C), 50% (group D), and 50% (group E), respectively. Five-year survival rates of the 5 groups were 85%, 93.8%, 80.6%, 50%, and 50%, respectively. CONCLUSIONS The TAR+FET technique is feasible and efficacious for aortic reoperation in patients who previously underwent cardiac surgery since the short-term mortality in patients with recurrent aortic arch disease after cardiac surgery is not high.
本研究旨在评估经正中胸骨切开术行心脏手术后再次发生主动脉疾病患者行全主动脉弓置换术联合冷冻象鼻技术(TAR+FET)的长期疗效。
我们对 118 例行 TAR+FET 的患者进行了研究,这些患者因先前的心脏手术而患有大血管疾病,并采用正中胸骨切开术。所有患者被分为 5 组:A 组患者先前的主要手术为主动脉瓣置换术(AVR);B 组患者先前的主要手术为升主动脉置换术;C 组患者先前的主要手术为主动脉根部置换术;D 组患者先前的主要手术为主动脉弓置换或介入治疗;E 组患者先前的主要手术为“其他”心脏手术。使用 Kaplan-Meier 法估计长期随访结果。
术后 30 天死亡率为 13.6%(16/118)-2 例死于 A 组,1 例死于 B 组,8 例死于 C 组,4 例死于 D 组,1 例死于 E 组。99%的患者完成了随访。平均随访时间为 47.6±36.3 个月,随访期间有 12 例患者死亡,因此总长期生存率为 76.3%。5 组患者的 1 年生存率分别为 85%(A 组)、93.8%(B 组)、82.3%(C 组)、50%(D 组)和 50%(E 组)。5 组患者的 5 年生存率分别为 85%、93.8%、80.6%、50%和 50%。
对于因心脏手术后再次发生主动脉弓疾病而需要再次手术的患者,TAR+FET 技术是可行且有效的,因为心脏手术后再次发生主动脉弓疾病的患者短期死亡率并不高。