Shrestha Malakh, Fleissner Felix, Ius Fabio, Koigeldiyev Nurbol, Kaufeld Tim, Beckmann Erik, Martens Andreas, Haverich Axel
Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Eur J Cardiothorac Surg. 2015 Feb;47(2):361-6; discussion 366. doi: 10.1093/ejcts/ezu185. Epub 2014 May 14.
Acute type A aortic dissection (AADA) is a surgical emergency. In patients with aortic arch and descending aorta (DeBakey type I) involvement, performing a total aortic arch replacement with frozen elephant trunk (FET) for supposedly better long-term results is controversial. We hereby present our results.
From February 2004 to August 2013, 52 patients with acute aortic dissection DeBakey type I received a FET procedure at our centre (43 males, age 59.21 ± 11.67 years). All patients had an intimal tear in the aortic arch and/or proximal descending aorta. Concomitant procedures were Bentall (n = 15) and aortic valve repair (n = 30).
Cardiopulmonary bypass (CPB), X-clamp and cardiac arrest times were 262 ± 64, 159 ± 45 and 55 ± 24 min, respectively. The 30-day mortality rate was 13% (n = 7). Stroke and re-thoracotomy for bleeding were 12% (n = 6) and 23% (n = 12), respectively. Postoperative recurrent nerve palsy and spinal cord injury rates were 10% (5 of 52) and 4% (2 of 52), respectively. Follow-up was 40 ± 24 months. During follow-up, no patient died and no patient required a reoperation for the aortic arch.
Our results with FET in AADA show acceptable results. Total aortic arch replacement with an FET in AADA patients does demand high technical skills. In spite of this, we believe FET improves long-term outcomes in cases of AADA with intima tear or re-entry in the aortic arch or the descending aorta (DeBakey type I). Modern grafts with four side branches as well as sewing collars for the distal anastomosis have helped to further 'simplify' the FET implantation. However, such a strategy is not appropriate in all AADA cases; it should be implemented only in experienced centres and only if absolutely necessary.
急性A型主动脉夹层(AADA)是一种外科急症。对于累及主动脉弓和降主动脉(DeBakey I型)的患者,采用带冰冻象鼻支架(FET)的全主动脉弓置换术以期获得更好的长期效果存在争议。我们在此展示我们的结果。
2004年2月至2013年8月,52例DeBakey I型急性主动脉夹层患者在我们中心接受了FET手术(43例男性,年龄59.21±11.67岁)。所有患者在主动脉弓和/或近端降主动脉有内膜撕裂。同期手术包括Bentall手术(n = 15)和主动脉瓣修复术(n = 30)。
体外循环(CPB)、阻断钳夹和心脏停搏时间分别为262±64、159±45和55±24分钟。30天死亡率为13%(n = 7)。中风和因出血再次开胸手术的发生率分别为12%(n = 6)和23%(n = 12)。术后喉返神经麻痹和脊髓损伤发生率分别为10%(52例中的5例)和4%(52例中的2例)。随访时间为40±24个月。随访期间,无患者死亡,也无患者因主动脉弓需要再次手术。
我们在AADA中使用FET的结果显示出可接受的效果。在AADA患者中使用FET进行全主动脉弓置换确实需要高技术水平。尽管如此,我们认为FET可改善伴有主动脉弓或降主动脉内膜撕裂或再入口的AADA(DeBakey I型)病例的长期预后。带有四个侧支的现代移植物以及用于远端吻合的缝合环有助于进一步“简化”FET植入。然而,这种策略并非适用于所有AADA病例;仅应在有经验的中心且绝对必要时实施。