Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing 100029, China.
Circulation. 2011 Mar 8;123(9):971-8. doi: 10.1161/CIRCULATIONAHA.110.015081. Epub 2011 Feb 21.
Appropriate surgical management of type A dissection is a critical factor for achieving satisfactory outcome, but the choice of optimal procedure is controversial. We retrospectively reviewed our experience with aortic arch replacement for type A dissection involving the arch.
Excluding 14 cases of subtotal or total aortic replacement, 411 of 544 patients with type A dissection (stented elephant trunk=291, conventional surgical repair=120) underwent aortic arch replacement between January 2003 and September 2008. In-hospital mortality was 3.09% (9 of 291) for stented (acute=4.73%, 7 of 148; chronic=1.40%, 2 of 143) and 5.00% (6 of 120) for conventional repairs (acute=6.06%, 4 of 66; chronic=3.70%, 2 of 54). Spinal cord injury was 2.41% (7 of 291) in the stented and 0.83% (1 of 120) in the conventional group. The overall prevalence of stroke was 1.95% (8 of 411) (stented=2.41%, 7 of 291; conventional=0.83, 1 of 120). Secondary intervention was 2.34% (5 of 214) for acute dissection (stented=1 and conventional=4; P=0.031) and 3.05% (6 of 197) for chronic dissection (stented=4 and conventional=2; P=0.661) during follow-up. Obliteration of the false lumen around the stented elephant trunk occurred in 94.2% (130 of 138) of patients with acute dissection and in 92.0% (126 of 137) of patients with chronic dissection.
Total arch replacement combined with stented elephant trunk implantation demonstrated the superiority of the combination of the surgical and interventional approaches while avoiding the weaknesses associated with the individual methods. The encouraging surgical results could enable this procedure to become the new "standard" therapy for type A dissection involving repair of the aortic arch.
A型夹层的适当外科治疗是获得满意结果的关键因素,但最佳手术方式仍存在争议。我们回顾性分析了累及主动脉弓的 A 型夹层患者行主动脉弓置换术的经验。
排除行次全或全主动脉置换术的 14 例患者,2003 年 1 月至 2008 年 9 月期间,544 例 A 型夹层患者(支架象鼻术=291 例,传统手术修复=120 例)中行主动脉弓置换术。支架象鼻术组(急性=4.73%,7/148;慢性=1.40%,2/143)和传统手术修复组(急性=6.06%,4/66;慢性=3.70%,2/54)住院死亡率分别为 3.09%(9/291)和 5.00%(6/120)。支架象鼻术组脊髓损伤发生率为 2.41%(7/291),传统手术修复组为 0.83%(1/120)。支架象鼻术组和传统手术修复组总体卒中发生率分别为 1.95%(8/411)(支架象鼻术=2.41%,7/291;传统手术修复=0.83%,1/120)。在随访期间,急性夹层组(支架象鼻术=1 例,传统手术修复=4 例;P=0.031)和慢性夹层组(支架象鼻术=4 例,传统手术修复=2 例;P=0.661)二次干预率分别为 2.34%(5/214)和 3.05%(6/197)。急性夹层患者中 94.2%(130/138)、慢性夹层患者中 92.0%(126/137)的支架象鼻周围假腔完全闭塞。
全主动脉弓置换术联合支架象鼻植入术显示出了手术与介入方法相结合的优势,同时避免了单一方法的不足。令人鼓舞的手术结果可能使该方法成为治疗累及主动脉弓的 A 型夹层的新“标准”治疗方法。