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多发伤患者行全身CT检查的合理性:临床检查能否有助于筛选患者?

Justification of whole-body CT in polytrauma patients, can clinical examination help selecting patients?

作者信息

Arora Richa, Arora Abhishek J

机构信息

Department of Radiology, Aintree University Hospital, Liverpool, UK.

Former Clinical MSK Fellow, Department of Radiology, Leeds Teaching Hospitals, Leeds, UK.

出版信息

Quant Imaging Med Surg. 2019 Apr;9(4):636-641. doi: 10.21037/qims.2019.04.02.

Abstract

BACKGROUND

Whole-body computed tomography (WBCT) is used indiscriminately in trauma cases, just on the suspicion of them being polytrauma cases. A good clinical examination done pre-emptively could prevent the need for this investigation and its undesirous effects. We did this study with an overall aim to assess, if WBCT can be limited to subgroup of trauma patients without compromising clinical safety.

METHODS

Retrospective database analysis of 150 cases of polytrauma who underwent WBCT in 2017 was performed. We recorded age, gender, radiation dose and CT findings in all cases and calculated mean age, number of total patients and female patients less than 25 years of age, number of normal WBCT scans, mean radiation dose in the normal and total scans. We also compared pre-test clinical requests with whole-body CT findings, and categorised them in following seven categories: Category 1-Normal Scans; Category 2-Clinically expected Major Injuries; Category 3-Clinically expected Minor Injuries (low risk injuries with no risk of morbidity or mortality if remained undiagnosed), Category 4-Clinically expected CT findings with unexpected Minor (non-serious) injuries; Category 5-Clinically expected CT findings with unexpected Major (serious) injuries, Category 6-Unexpected Minor (non-serious) injuries; Category 7-Unexpected Major (serious) injuries. Categories 2 &3 of clinically expected major and minor injuries included patients with fewer injuries than expected. On the other hand, Category 4 & 5 consist of clinically expected findings with other unexpected injuries, including minor and major injuries respectively. Body injuries were reported in seven areas as per our institutional reporting protocol- Head (including face), Cervical Spine, Thoracolumbar Spine, Chest, Abdomen, Pelvis and Appendicular Skeleton (if asked for).

RESULTS

Overall, we found statistically significant correlation between clinical suspicion raised and WBCT findings with good clinical correlation noticed in 106 (70.66%) cases (including 61 cases of clinically suspected major injuries, 15 cases of clinically suspected minor injuries and 25 nearly normal scans with no obvious clinical concern). Isolated unexpected serious injury without any clinical suspicion was seen in only 1 case. Surprisingly, 25 scan requests were made due to high risk mechanism of injury with no obvious clinical concern and were found normal in 20 cases and showed very subtle injuries in 5. Notably, 30 cases of expected major and minor injuries showed highly accurate clinical findings with no injury other than the region of concern and in these cases, limited scan requests would have been sufficient. Mean radiation dose of the entire study group was 22.45 mSv and those to normal patients was 21.19 mSv.

CONCLUSIONS

This study re-emphasizes the significance of good clinical examination in the era of evidence based medicine, which would reduce the high number of unnecessary high dose WBCT (25 scans with no positive findings on clinical examination were nearly normal and in 30 cases limited CT would have been sufficient), thereby, decreasing radiation exposure and its potential side effects on polytrauma patients without affecting their survival.

摘要

背景

在创伤病例中,全身计算机断层扫描(WBCT)被不加区分地使用,仅仅是怀疑患者为多发伤病例。预先进行全面的临床检查可以避免进行此项检查及其不良影响。我们开展这项研究的总体目的是评估,在不影响临床安全性的前提下,WBCT是否可以局限于创伤患者的亚组。

方法

对2017年接受WBCT检查的150例多发伤病例进行回顾性数据库分析。我们记录了所有病例的年龄、性别、辐射剂量和CT检查结果,并计算了平均年龄、患者总数、年龄小于25岁的女性患者数量、正常WBCT扫描的数量、正常扫描和全部扫描的平均辐射剂量。我们还将检查前的临床诊断需求与全身CT检查结果进行了比较,并将其分为以下七类:第1类——正常扫描;第2类——临床预期的严重损伤;第3类——临床预期的轻微损伤(低风险损伤,若未诊断出来不会有发病或死亡风险);第4类——临床预期的CT检查结果伴有意外的轻微(不严重)损伤;第5类——临床预期的CT检查结果伴有意外的严重(严重)损伤;第6类——意外的轻微(不严重)损伤;第7类——意外的严重(严重)损伤。临床预期的严重和轻微损伤的第2类和第3类包括损伤比预期少的患者。另一方面,第4类和第5类包括临床预期的检查结果伴有其他意外损伤,分别为轻微和严重损伤。根据我们机构的报告方案,身体损伤在七个部位进行报告——头部(包括面部)、颈椎、胸腰椎、胸部、腹部、骨盆和附属骨骼(如有要求)。

结果

总体而言,我们发现临床怀疑与WBCT检查结果之间存在统计学上的显著相关性,106例(70.66%)病例具有良好的临床相关性(包括61例临床怀疑严重损伤、15例临床怀疑轻微损伤以及25例几乎正常且无明显临床问题的扫描)。仅1例出现了无任何临床怀疑的孤立性意外严重损伤。令人惊讶的是,25例扫描申请是由于高风险损伤机制且无明显临床问题而提出的,其中20例检查结果正常,5例显示非常轻微的损伤。值得注意的是,30例预期的严重和轻微损伤显示出高度准确的临床检查结果,除了关注区域外没有其他损伤,在这些病例中,有限的扫描申请就足够了。整个研究组的平均辐射剂量为22.45 mSv,正常患者为为21.19 mSv。

结论

这项研究再次强调了在循证医学时代全面临床检查的重要性,这将减少大量不必要的高剂量WBCT检查(25例临床检查无阳性发现的扫描几乎正常,30例病例进行有限的CT检查就足够了),从而减少辐射暴露及其对多发伤患者的潜在副作用,同时不影响患者的生存率。

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