Department of Trauma and Orthopaedic Surgery, Division of Orthopeadics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Department of Paediatric Surgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.
Injury. 2024 May;55(5):111494. doi: 10.1016/j.injury.2024.111494. Epub 2024 Mar 11.
Whole-Body CT (WBCT) is frequently used in emergency situations for promptly diagnosing paediatric polytrauma patients, given the challenges associated with obtaining precise details about the mechanism and progression of trauma. However, WBCT does not lead to reduced mortality in paediatric patients, but is associated with high radiation exposure. We therefore wanted to develop a screening tool for CT demand-driven emergency room (ER)-trauma diagnostic to reduce radiation exposure in paediatric patients.
A retrospective study in a Level I trauma centre in Germany was performed. Data from 344 paediatric emergency patients with critical mechanism of injury who were pre-announced by the ambulance for the trauma room were collected. Patients' symptoms, clinical examination, extended Focused Assessment with Sonography for Trauma (eFAST), routinely, laboratory tests and blood gas and - when obtained - WBCT images were analysed. To identify potential predictors of severe injuries (ISS > 23), 300 of the 344 cases with complete data were subjected to regression analyses model.
Multiple regression analysis identified cGCS, base excess (BE), medically abnormal results from eFAST screening, initial unconsciousness, and injuries involving three or more body regions as significant predictors for a screening tool for decision-making to perform WBCT or selective CT. The developed Paediatric polytrauma CT-Indication (PePCI)-Score was divided into three risk categories and achieved a sensitivity of 87 % and a specificity of 71 % when comparing the low and medium risk groups with the high risk group. Comparing only the low-risk group with the high-risk group for the decision to perform WBCT, 32/35 (91 %) of patients with an ISS >23 were correctly identified, as were 124/137 (91 %) with lower ISS scores.
With the newly developed PePCI-Score, the frequency of WBCT in a paediatric emergency patients collective can be significantly reduced according to our data. After prospective validation, the initial assessment of paediatric trauma patients in the future could be made not only by the mechanism of injury, but also by the new PePCI-Score, deriving on clinical findings after thorough clinical assessment and the discretion of the trauma team.
鉴于获取创伤机制和进展的确切细节存在挑战,全身 CT(WBCT)常用于紧急情况下对儿科多发伤患者进行快速诊断。然而,WBCT 并未降低儿科患者的死亡率,但与高辐射暴露有关。因此,我们希望开发一种 CT 需求驱动的急诊室(ER)-创伤诊断筛查工具,以降低儿科患者的辐射暴露。
在德国的一家一级创伤中心进行了一项回顾性研究。收集了由救护车预通知进入创伤室的 344 名严重创伤机制的儿科急诊患者的数据。分析了患者的症状、临床检查、扩展的创伤超声重点评估(eFAST)、常规实验室检查和血气检查,以及在获得时的全身 CT 图像。为了确定严重损伤(ISS>23)的潜在预测因素,对 344 例具有完整数据的病例中的 300 例进行了回归分析模型。
多元回归分析确定了 cGCS、基础不足(BE)、eFAST 筛查的医学异常结果、初始无意识和涉及三个或更多身体区域的损伤作为进行 WBCT 或选择性 CT 决策的筛查工具的显著预测因素。开发的小儿多发伤 CT 指征(PePCI)评分分为三个风险类别,当将低风险和中风险组与高风险组进行比较时,敏感性为 87%,特异性为 71%。仅比较低风险组与高风险组进行 WBCT 决策,ISS>23 的 35 例患者中有 32 例(91%)得到正确识别,ISS 较低的 137 例患者中有 124 例(91%)得到正确识别。
根据我们的数据,使用新开发的 PePCI 评分,可以显著降低儿科急诊患者群体中 WBCT 的频率。经过前瞻性验证后,未来对儿科创伤患者的初步评估不仅可以通过损伤机制进行,还可以通过新的 PePCI 评分进行,该评分基于全面临床评估后的临床发现和创伤团队的判断力。