Division of Musculoskeletal and Rheumatic Disorders, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Calzada Mexico-Xochimilco 289 Colonia Arenal de Guadalupe, 14389, Mexico City, CP, Mexico.
Division of Neurosciences, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico City, Mexico.
Clin Rheumatol. 2019 Sep;38(9):2595-2602. doi: 10.1007/s10067-019-04614-1. Epub 2019 May 29.
INTRODUCTION/OBJECTIVES: The prevalence of chondrocalcinosis (CC) was reported as variable according to the geographic populations. However, there are no data regarding its prevalence in Mexico. Thus, we decided to investigate the Mexican prevalence of CC in a cohort of patients from a tertiary health care institution.
A retrospective analysis of radiographs of knees and wrists from our institution was performed. Inclusion criteria included patients > 50 years old having radiographs of knees and wrists. Radiographic presence of CC was classified according to a dichotomous evaluation assayed by two rheumatologists experts on the area.
A total of 3.350 radiographs from 1.602 patients were evaluated. Forty-seven patients showed calcifications in at least one knee or wrist for an overall prevalence of 3%, of which 23.4% were men and 76.6% women. The knee was more commonly affected than the wrist (85.1% and 14.9% respectively). The prevalence according to gender was 2.9% in women, whereas, it was 3.2% in men. Only two patients (4.3%) showed a contemporaneous presence of CC in both hands and both knees. At knee level, the prevalence was 2.7%, whereas at the wrist, we reported a prevalence of 4.9%.
The prevalence of CC for Mexican population had not been reported so far. This a starting point to break the silence and encourage the knowledge of how this disease is associated with possible risk factors in Mexican population. Key Points •The prevalence of chondrocalcinosis in Mexico was 3%. •The prevalence of knee chondrocalcinosis increases according to the age in women's. •The nixtamalized meals could be a protective factor for CC in Mexican population.
简介/目的:根据地理人群的不同,软骨钙质沉着症(CC)的患病率报道各不相同。然而,关于墨西哥的患病率数据尚不清楚。因此,我们决定在一家三级医疗机构的患者队列中调查 CC 在墨西哥的流行情况。
对我们机构的膝关节和腕关节的射线照片进行了回顾性分析。纳入标准包括年龄>50 岁且有膝关节和腕关节射线照片的患者。根据两名风湿病专家在该领域的双盲评估,将 CC 的放射学表现分为二分类评估。
共评估了 1602 名患者的 3350 张射线照片。47 名患者至少在一只膝关节或腕关节有钙化,总体患病率为 3%,其中 23.4%为男性,76.6%为女性。膝关节比腕关节更常受累(分别为 85.1%和 14.9%)。女性的患病率为 2.9%,而男性为 3.2%。只有两名患者(4.3%)同时在手和膝关节都存在 CC。在膝关节水平,患病率为 2.7%,而在腕关节,我们报告的患病率为 4.9%。
迄今为止,墨西哥人群的 CC 患病率尚未报道。这是打破沉默并鼓励了解这种疾病如何与墨西哥人群中的可能危险因素相关的起点。
墨西哥软骨钙质沉着症的患病率为 3%。
女性膝关节软骨钙质沉着症的患病率随年龄增长而增加。
墨西哥玉米粉蒸肉可能是 CC 的保护因素。