Petty T L
Mayo Clin Proc. 1987 Sep;62(9):841-7. doi: 10.1016/s0025-6196(12)62339-8.
Clinical applications for the use of oxygen have extended beyond the hospital setting to home therapy. In patients with hypoxemic chronic obstructive pulmonary disease, long-term administration of oxygen has been substantiated as beneficial in terms of improved survival, decreased hospitalization, increased exercise capability and endurance, enhanced neuropsychologic function, and alleviation of hemodynamic abnormalities. Continuous oxygen therapy with use of an ambulatory system consistently provides the greatest benefit. New developments that have facilitated home oxygen therapy are conservation methods that allow flow of oxygen only during inspiration or storage of oxygen during expiration and cosmetic improvements for concealing devices used to administer oxygen. Controlled studies are needed to determine the optimal duration and method of administration of oxygen and the selection of appropriate candidates for long-term home oxygen therapy.
氧气的临床应用已从医院环境扩展到家庭治疗。在低氧性慢性阻塞性肺疾病患者中，长期吸氧已被证实有益，可提高生存率、减少住院次数、增强运动能力和耐力、改善神经心理功能以及缓解血液动力学异常。使用便携式系统进行持续氧疗始终能带来最大益处。促进家庭氧疗发展的新进展包括仅在吸气时供氧或在呼气时储存氧气的节约方法，以及用于隐藏吸氧设备的外观改进。需要进行对照研究以确定氧气给药的最佳持续时间和方法，以及为长期家庭氧疗选择合适的患者。
