Shade Brandon C, Melchior Richard W, Fisher Douglas R, High Robin, Mascio Christopher E, Rosenthal Tami M, Holt David W
Department of Perfusion Services, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA.
Perfusion. 2020 Jan;35(1):26-31. doi: 10.1177/0267659119850344. Epub 2019 May 31.
Vacuum-assisted venous drainage has gained widespread use within the pediatric perfusion community for use during cardiopulmonary bypass. It is questioned whether its efficiency may be compromised with application of excessive cardiotomy suction to the infant hard-shell venous reservoir. An in vitro simulation circuit was used to research this phenomenon. A comparison of three different infant hard-shell venous reservoirs also took place to determine if one reservoir type was more advantageous when handling cardiotomy suction. The reservoirs tested were the Maquet VHK 11000, Medtronic Affinity Pixie, and Terumo Capiox FX05.
The in vitro simulation circuit consisted of a 1 L reservoir bag that was cannulated at one access point with an Edwards Lifesciences 10Fr aortic cannula and the other access area with an Edwards Lifesciences 10Fr right angle venous cannula and 12Fr right angle venous cannula that were joined together. Key points of measurement and response variables were the pressures on the connection of the venous cannulas, inlet of the venous reservoir, and flow through the venous line. Vacuum was applied and manipulated with a Maquet VAVD Controller to settings of -20 mmHg, -30 mmHg, -40 mmHg, -50 mmHg, and -60 mmHg. Cardiotomy suction was added at settings of 1 LPM, 2 LPM, 3 LPM, and 4 LPM. Values from each response variable were monitored and recorded. These data were utilized to compare the reservoirs with a random coefficient model for each response variable.
There is an adverse effect of excessive cardiotomy suction on the efficacy of vacuum-assisted venous drainage in infant hard-shell venous reservoirs. There is no significant difference between the VHK 11000, Pixie, and FX05 regarding their ability to handle this occurrence. An important discovery was that the FX05 showed a greater transfer of vacuum to the venous cannulas and reservoir inlet.
真空辅助静脉引流在小儿体外循环灌注领域已得到广泛应用。有人质疑,在婴儿硬壳静脉储血器上过度使用心内吸引是否会损害其效率。为此,采用体外模拟回路对这一现象进行了研究。同时,对三种不同的婴儿硬壳静脉储血器进行了比较,以确定在处理心内吸引时,是否有一种储血器类型更具优势。所测试的储血器分别是迈柯唯VHK 11000、美敦力Affinity Pixie和泰尔茂Capiox FX05。
体外模拟回路由一个1升的储血袋组成,在一个接入点用爱德华生命科学公司的10Fr主动脉插管进行插管,在另一个接入区域用爱德华生命科学公司的10Fr直角静脉插管和12Fr直角静脉插管连接在一起。测量的关键点和反应变量是静脉插管连接处、静脉储血器入口处的压力以及通过静脉管路的流量。使用迈柯唯VAVD控制器施加并调节真空,设置为-20 mmHg、-30 mmHg、-40 mmHg、-50 mmHg和-60 mmHg。在心内吸引设置为1 LPM、2 LPM、3 LPM和4 LPM的情况下添加心内吸引。监测并记录每个反应变量的值。利用这些数据,通过随机系数模型对每个反应变量的储血器进行比较。
过度的心内吸引对婴儿硬壳静脉储血器中真空辅助静脉引流的效果有不利影响。VHK 11000、Pixie和FX05在处理这种情况的能力方面没有显著差异。一个重要的发现是,FX05向静脉插管和储血器入口处传递的真空更大。