Viala D, Viala G, Persegol L, Palisses R
Neurosci Lett. 1987 Aug 5;78(3):318-22. doi: 10.1016/0304-3940(87)90380-6.
Phrenic bursting resulting from locomotor entrainment during fictive locomotion was shown previously in high spinal preparation after nialamide-DOPA administration. The temporal evolution of the bilateral pattern of phrenic vs locomotor activity is considered here. At variance with the bilateral locomotor pattern which is always alternate (fictive stepping), the pattern on both phrenic nerves changes with time after DOPA injection: first alternate, left and right phrenic bursts become synchronous. A study of ipsilateral phrenic-locomotor phase relationships allowed to disclose the way the transition from alternate to synchronous phrenic coupling was achieved: synchronism appeared as resulting from a strong facilitation on the overlapping parts of the bilaterally alternating phrenic bursts; this phase shifting, vs the ipsilateral locomotor pattern, accounts for the transfer of phrenic bilateral coupling.
先前在给予尼亚酰胺 - 多巴后高位脊髓制备中已显示，在虚拟运动期间运动夹带导致的膈神经爆发。在此考虑膈神经与运动活动双边模式的时间演变。与始终交替的双边运动模式（虚拟踏步）不同，多巴注射后双侧膈神经上的模式随时间变化：起初是交替的，左右膈神经爆发变为同步。对同侧膈神经 - 运动相位关系的研究揭示了从交替膈神经耦合到同步膈神经耦合的转变方式：同步似乎是由于双侧交替膈神经爆发重叠部分的强烈促进作用；相对于同侧运动模式的这种相位偏移解释了膈神经双边耦合的转变。
