Viala D, Vidal C, Freton E
Neurosci Lett. 1979 Feb;11(2):155-9. doi: 10.1016/0304-3940(79)90119-8.
In unanaesthetized, curarized spinal rabbits (C2 level) treated with Niamide and DOPA, rhythmic activities were recorded from the phrenic nerves; close coordination was observed between the phrenic bursts and the locomotor bursts which developed in hindlimb muscle nerves. The frequency of phrenic bursts was reduced after a second spinal transection at the Th12 level, while rhythms in the hindlimb remained unchanged. It thus appears that in the spinal preparation and under certain pharmacological conditions, phrenic bursts generated by the cervico-thoracic spinal cord can be driven by the lumbar generators of locomotion; spinal links thus exist between these hindlimb locomotion generators and spinal interneuronal networks involved in phrenic motoneuronal activation, may be via hindlimb forelimb driving.
在未麻醉、用箭毒处理的脊髓兔（C2水平）中，用尼亚酰胺和多巴进行处理后，从膈神经记录到节律性活动；观察到膈神经冲动与后肢肌肉神经中出现的运动神经冲动之间有密切协调。在胸12水平进行第二次脊髓横断后，膈神经冲动的频率降低，而后肢的节律保持不变。因此，似乎在脊髓制备及某些药理学条件下，颈胸段脊髓产生的膈神经冲动可由腰段运动发生器驱动；这些后肢运动发生器与参与膈运动神经元激活的脊髓中间神经元网络之间存在脊髓联系，可能是通过后肢对前肢的驱动。
