Shah Bela J, Mistry Deval, Chaudhary Navin
Department of Dermatology, B J Medical College, Civil Hospital, Ahmedabad, Gujarat, India.
Indian J Dermatol. 2019 May-Jun;64(3):242-244. doi: 10.4103/ijd.IJD_633_18.
Psoriasis is a chronic papulosquamous skin disease that involves immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. The associated immunosuppression in people living with HIV (PLHIV) with psoriasis poses a challenge to the clinician as therapeutic options are limited. Until now, there have been no documented case of apremilast therapy for HIV-associated psoriasis in India. Here, we report a case of HIV-associated psoriasis who achieved Psoriasis Area and Severity Index (PASI) 100 with apremilast therapy.
银屑病是一种慢性丘疹鳞屑性皮肤病，涉及免疫介导的皮肤炎症和角质形成细胞过度增殖。感染人类免疫缺陷病毒（HIV）的银屑病患者存在相关免疫抑制，这给临床医生带来了挑战，因为治疗选择有限。到目前为止，印度尚无关于阿普米司特治疗HIV相关性银屑病的病例报道。在此，我们报告一例HIV相关性银屑病患者，通过阿普米司特治疗实现了银屑病面积和严重程度指数（PASI）达到100。
