Torbay and South Devon Integrated Care Trust, Torquay.
West Suffolk District General Hospital, Bury St Edmunds, UK.
Diabet Med. 2019 Nov;36(11):1424-1430. doi: 10.1111/dme.14045. Epub 2019 Jun 17.
To ascertain the effects of improvements in diabetic foot services over 18 years on incidence of diabetic foot ulceration. We also compared survival time from first ulcer development with presence of neuropathy, peripheral vascular disease, age and healing.
Persons with new ulceration and those at high risk of ulcer development were referred to community podiatry from 1998. Their details were recorded, with verbal consent, on a central database. The effects of neuropathy, peripheral vascular disease, healing and age on survival were analysed by Cox proportional hazards ratios.
The incidence of first ulcer presentation decreased from 11.1 to 6.1 per 1000 persons between 2003 to 2017 (P <0.0001). Recurrent ulceration incidence remained stable. Prevalence of chronic and new foot ulceration combined increased from 20.7 to 33.1 per 1000 persons (P <0.0001). Ten-year survival was 85% for persons presenting with first ulcer and aged < 65 years, 50% for those aged 65-74 years and 25% for those aged 75-81 years (P < 0.0001). In those with peripheral vascular disease 5-year survival was 35% (P <0.001).
Integrated care for the diabetic foot in one National Health Service (NHS) health service area over 18 years was associated with a reduction in first presentations of diabetic foot ulceration, but failed to reduce recurrent ulceration. Cumulative prevalence of all ulcers continues to increase. Monitoring ulceration incidence can inform audit and planning of diabetic foot care services. Survival is better than reported previously in persons < 65 years and in the absence of peripheral vascular disease.
确定 18 年来糖尿病足服务改善对糖尿病足溃疡发生率的影响。我们还比较了首次溃疡发展时伴有神经病变、外周血管疾病、年龄和愈合情况的生存时间。
1998 年起,有新发溃疡和高溃疡发展风险的患者被转诊至社区足病科。他们的详细信息在中央数据库中进行了记录,并征得口头同意。通过 Cox 比例风险比分析了神经病变、外周血管疾病、愈合和年龄对生存的影响。
2003 年至 2017 年期间,首次溃疡发作的发病率从每 1000 人 11.1 例降至 6.1 例(P<0.0001)。复发性溃疡的发病率保持稳定。慢性和新发足部溃疡的总患病率从每 1000 人 20.7 例增加到 33.1 例(P<0.0001)。首次出现溃疡且年龄<65 岁的患者 10 年生存率为 85%,年龄 65-74 岁的患者为 50%,年龄 75-81 岁的患者为 25%(P<0.0001)。患有外周血管疾病的患者 5 年生存率为 35%(P<0.001)。
在一个国家医疗服务体系(NHS)健康服务区内,对糖尿病足进行 18 年的综合护理与首次糖尿病足溃疡发作的减少有关,但未能减少复发性溃疡。所有溃疡的累积患病率仍在继续增加。监测溃疡发病率可以为糖尿病足护理服务的审核和规划提供信息。生存率优于此前报道的<65 岁患者和无外周血管疾病患者的生存率。