Rothlin M E
Schweiz Med Wochenschr. 1979 Feb 10;109(6):183-5.
The literature on the influence of aortocoronary bypass surgery is reviewed with respect to life expectancy and symptoms. Preliminary results of the European prospective randomized coronary study are also presented. There was no significant difference in clinical or angiographic criteria as between the medically and surgically treated patient groups. For the total cohorts, survival did not significantly differ, though in patients with 3-vessel disease, mortality was significantly higher in the medically treated group. This observation requires confirmation before it is allowed to influence our decisions. In the same prospective trial, surgery improved symptoms in 4/5 of the patients and eliminated angina in half. With medical treatment, fewer than half of the patients experienced further improvement during the same time period and only 15% became symptom-free.
本文就主动脉冠状动脉搭桥手术对预期寿命和症状的影响相关文献进行了综述。同时还介绍了欧洲前瞻性随机冠状动脉研究的初步结果。在内科治疗组和外科治疗组患者之间,临床或血管造影标准方面没有显著差异。对于所有队列而言,生存率没有显著差异,不过在三支血管病变的患者中,内科治疗组的死亡率显著更高。这一观察结果在影响我们的决策之前需要得到证实。在同一前瞻性试验中,手术改善了五分之四患者的症状,半数患者心绞痛消失。接受内科治疗的患者中,在同一时期内症状进一步改善的不到半数,只有15%的患者症状消失。