Suppr超能文献

减重手术后的早期心脏并发症:手术类型重要吗?

Early cardiac complications after bariatric surgery: does the type of procedure matter?

机构信息

Department of Surgery, College of Medicine, University of Oklahoma, Tulsa, Oklahoma.

Department of Surgery, College of Medicine, University of Oklahoma, Tulsa, Oklahoma.

出版信息

Surg Obes Relat Dis. 2019 Jul;15(7):1132-1137. doi: 10.1016/j.soard.2019.03.030. Epub 2019 Mar 23.

Abstract

BACKGROUND

Major adverse cardiac events (MACE) can be a cause of postoperative mortality. This is specifically important in bariatric surgery due to obesity-related cardiovascular risk factors.

OBJECTIVE

To assess postoperative cardiac adverse events after bariatric surgery and its independent predictors.

SETTING

A retrospective analysis of 2011-2015 Healthcare Cost and Utilization Project-National Inpatient Sample.

METHODS

Data on patients who underwent laparoscopic sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) were retrieved. MACE was identified as a composite variable including myocardial infarction, acute ischemic heart disease without myocardial infarction, and acute heart failure. Dysrhythmia (excluding premature beats) was identified as a separate outcome. Multivariate regression analysis for MACE was performed using demographic factors, co-morbidities, and type of surgery.

RESULTS

The analysis included 108,432 patients (SG: 54.6%, RYGB: 45.4%). MACE was found in 116 patients (.1%), and dysrhythmia occurred in 3670 patients (3.4%). Median length of stay in patients with MACE was 4.5 versus 2 days in others (P < .001). There were 43 deaths overall, and 31 were in patients with MACE or dysrhythmia (P < .001). Age ≥ 50 years, male sex, congestive heart failure, chronic pulmonary disease, ischemic heart disease, history of pulmonary emboli, and fluid or electrolyte disorders were independent predictors of MACE based on multivariate analysis. Type of surgery (SG versus RYGB) was not an independent predictor for MACE (odds ratio 1.41, 95% confidence interval: .77-2.55).

CONCLUSIONS

While cardiac complications are rare after bariatric surgery, their occurrence is associated with increased length of stay, hospital charges, and mortality. Older age, male sex, cardiopulmonary co-morbidities, and fluid or electrolyte disorders are predictive of MACE. RYGB does not increase the risk of MACE compared with SG.

摘要

背景

主要心脏不良事件(MACE)可能是术后死亡的一个原因。由于肥胖相关的心血管危险因素,这在减重手术中尤为重要。

目的

评估减重手术后的心脏不良事件及其独立预测因素。

设置

对 2011 年至 2015 年医疗保健成本和利用项目-全国住院患者样本进行回顾性分析。

方法

检索接受腹腔镜袖状胃切除术(SG)或 Roux-en-Y 胃旁路术(RYGB)的患者数据。MACE 被确定为包括心肌梗死、无心肌梗死的急性缺血性心脏病和急性心力衰竭的复合变量。心律失常(不包括早搏)被确定为单独的结果。使用人口统计学因素、合并症和手术类型对 MACE 进行多变量回归分析。

结果

该分析包括 108432 名患者(SG:54.6%,RYGB:45.4%)。116 名患者(.1%)发生 MACE,3670 名患者(3.4%)发生心律失常。MACE 患者的中位住院时间为 4.5 天,而其他患者为 2 天(P<.001)。共有 43 例死亡,其中 31 例发生在 MACE 或心律失常患者中(P<.001)。多变量分析显示,年龄≥50 岁、男性、充血性心力衰竭、慢性肺部疾病、缺血性心脏病、肺栓塞史以及液体或电解质紊乱是 MACE 的独立预测因素。手术类型(SG 与 RYGB)不是 MACE 的独立预测因素(比值比 1.41,95%置信区间:.77-2.55)。

结论

虽然减重手术后心脏并发症罕见,但它们的发生与延长住院时间、增加住院费用和增加死亡率相关。年龄较大、男性、心肺合并症以及液体或电解质紊乱是 MACE 的预测因素。与 SG 相比,RYGB 不会增加 MACE 的风险。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验