Bespoke Babies: Genome Editing in Cystic Fibrosis Embryos.
作者信息
Brothers Kyle B, Devereaux Mary, Sade Robert M
机构信息
Division of Pediatric Clinical and Translational Research, Department of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky; Institute for Bioethics, Health Policy, and Law, University of Louisville School of Medicine, Louisville, Kentucky.
Research Ethics Program, Department of Pathology, University of California San Diego, La Jolla, California; Bioethics Program, Rady Children's Hospital of San Diego, San Diego, California.
出版信息
Ann Thorac Surg. 2019 Oct;108(4):995-999. doi: 10.1016/j.athoracsur.2019.04.030. Epub 2019 May 29.
Abstract
摘要
相似文献
1
Bespoke Babies: Genome Editing in Cystic Fibrosis Embryos.定制婴儿：囊性纤维化胚胎的基因编辑
Ann Thorac Surg. 2019 Oct;108(4):995-999. doi: 10.1016/j.athoracsur.2019.04.030. Epub 2019 May 29.
2
Gene editing & stem cells.基因编辑与干细胞。
J Cyst Fibros. 2018 Jan;17(1):10-16. doi: 10.1016/j.jcf.2017.11.018. Epub 2017 Dec 9.
3
Laying the Foundation for Cystic Fibrosis Therapy: An Interview with Michael Boyle.为囊性纤维化治疗奠定基础：对迈克尔·博伊尔的采访
Hum Gene Ther. 2020 Sep;31(17-18):917-920. doi: 10.1089/hum.2020.29134.int. Epub 2020 Sep 11.
4
Fixing stem cells via genome editing: hope for cystic fibrosis?通过基因组编辑修复干细胞：囊性纤维化的希望？
Regen Med. 2016 Jan;11(1):1-3. doi: 10.2217/rme.15.84. Epub 2015 Dec 18.
5
Gene editing flows to the lungs.基因编辑流向肺部。
Science. 2024 Jun 14;384(6701):1175-1176. doi: 10.1126/science.adq0059. Epub 2024 Jun 13.
6
Gene Therapy for Respiratory Diseases: Progress and a Changing Context.呼吸系统疾病的基因治疗：进展与不断变化的背景
Hum Gene Ther. 2020 Sep;31(17-18):911-916. doi: 10.1089/hum.2020.142.
7
Correcting CFTR: New Gene Editing Strategies for Rescuing CFTR Function Ex Vivo.体外纠正 CFTR：新的基因编辑策略用于恢复 CFTR 功能
Cell Stem Cell. 2020 Apr 2;26(4):476-478. doi: 10.1016/j.stem.2020.03.012.
8
delta F508 in cystic fibrosis: willing but not able.囊性纤维化中的ΔF508：有心无力。
Arch Dis Child. 1997 Mar;76(3):278-82. doi: 10.1136/adc.76.3.278.
9
New therapies in cystic fibrosis.囊性纤维化的新疗法。
Curr Pharm Des. 2012;18(5):614-27. doi: 10.2174/138161212799315984.
10
Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease.用于囊性纤维化相关肺部疾病的局部囊性纤维化跨膜传导调节因子基因替代疗法。
Paediatr Respir Rev. 2017 Mar;22:47-49. doi: 10.1016/j.prrv.2016.10.005. Epub 2016 Nov 5.
引用本文的文献
1
Advancing the Battle against Cystic Fibrosis: Stem Cell and Gene Therapy Insights.推进对抗囊性纤维化的战斗：干细胞与基因治疗见解
Curr Med Sci. 2024 Dec;44(6):1155-1174. doi: 10.1007/s11596-024-2936-5. Epub 2024 Dec 16.
2
Clinical Trial Design for Disease-Modifying Therapies for Genetic Epilepsies.遗传性癫痫的疾病修饰疗法的临床试验设计。
Neurotherapeutics. 2021 Jul;18(3):1445-1457. doi: 10.1007/s13311-021-01123-5. Epub 2021 Sep 30.
3
Human genome editing and the identity politics of genetic disability.人类基因组编辑与遗传残疾的身份政治
J Community Genet. 2020 Apr;11(2):125-127. doi: 10.1007/s12687-019-00437-4. Epub 2019 Sep 6.
本文引用的文献
1
Shock greets claim of CRISPR-edited babies.“基因编辑婴儿”声明引发轩然大波。
Science. 2018 Nov 30;362(6418):978-979. doi: 10.1126/science.362.6418.978.
2
Cystic Fibrosis Mortality in Childhood. Data from European Cystic Fibrosis Society Patient Registry.儿童囊性纤维化死亡率。来自欧洲囊性纤维化协会患者登记处的数据。
Int J Environ Res Public Health. 2018 Sep 15;15(9):2020. doi: 10.3390/ijerph15092020.
3
Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.CRISPR-Cas9 诱导的双链断裂的修复会导致大片段缺失和复杂重排。
Nat Biotechnol. 2018 Sep;36(8):765-771. doi: 10.1038/nbt.4192. Epub 2018 Jul 16.
4
Rethink public engagement for gene editing.重新思考基因编辑的公众参与。
Nature. 2018 Mar 22;555(7697):438-439. doi: 10.1038/d41586-018-03269-3.
5
U.S. attitudes on human genome editing.美国对人类基因组编辑的态度。
Science. 2017 Aug 11;357(6351):553-554. doi: 10.1126/science.aan3708.
6
Human Germline Genome Editing.人类种系基因组编辑
Am J Hum Genet. 2017 Aug 3;101(2):167-176. doi: 10.1016/j.ajhg.2017.06.012.
7
A systematic review of factors associated with health-related quality of life in adolescents and adults with cystic fibrosis.对患有囊性纤维化的青少年和成年人中与健康相关生活质量相关因素的系统评价。
Ann Am Thorac Soc. 2015 Mar;12(3):420-8. doi: 10.1513/AnnalsATS.201408-393OC.
8
Diabetes-related mortality in adults with cystic fibrosis. Role of genotype and sex.成年囊性纤维化患者的糖尿病相关死亡率。基因型和性别的作用。
Am J Respir Crit Care Med. 2015 Jan 15;191(2):194-200. doi: 10.1164/rccm.201403-0576OC.
9
A contemporary survival analysis of individuals with cystic fibrosis: a cohort study.当代囊性纤维化患者的生存分析：队列研究。
Eur Respir J. 2015 Mar;45(3):670-9. doi: 10.1183/09031936.00119714. Epub 2014 Nov 13.
10
Zinc finger nuclease technology heralds a new era in mammalian transgenesis.锌指核酸酶技术开创了哺乳动物转基因的新时代。
Trends Biotechnol. 2010 Mar;28(3):134-41. doi: 10.1016/j.tibtech.2009.11.007. Epub 2009 Dec 16.
Zotero 插件