进化性别分配理论解释了自然感染疟原虫中的性别比例。
Evolutionary sex allocation theory explains sex ratios in natural Plasmodium falciparum infections.
机构信息
Institute of Evolutionary Biology & Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, United Kingdom.
College of Medicine and Health Sciences, Sultan Qaboos University, PO Box 35, Alkhoud 123, Oman.
出版信息
Int J Parasitol. 2019 Jul;49(8):601-604. doi: 10.1016/j.ijpara.2019.04.001. Epub 2019 May 31.
Abstract
Malaria transmission is achieved by sexual stages, called gametocytes, and the proportion of gametocytes that are male versus female (sex ratio) influences transmission success. In malaria model systems, variation in gametocyte sex ratios can be explained by the predictions of evolutionary sex allocation theory. We test these predictions using natural Plasmodium falciparum infections. The predicted negative correlation between sex ratio and gametocyte density holds: the sex ratio increases when gametocyte densities decrease, and this is most apparent in single genotype infections and in the dry season. We do not observe higher gametocyte sex ratios in mixed compared with single genotype infections.
摘要
疟疾通过有性阶段（称为配子体）传播，配子体中雄性配子体与雌性配子体的比例（性别比例）会影响传播的成功率。在疟疾模型系统中，配子体性别比例的变化可以用进化性别分配理论的预测来解释。我们利用自然感染的恶性疟原虫来验证这些预测。性别比例与配子体密度之间呈负相关的预测结果成立：当配子体密度下降时，性别比例会上升，这在单一基因型感染和旱季中最为明显。我们没有观察到混合感染比单一基因型感染有更高的配子体性别比例。
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