曾接受二极管激光治疗1型早产儿视网膜病变的儿童中的带状角膜病变。
Band keratopathy in children previously treated with diode laser for type 1 retinopathy of prematurity.
作者信息
Ali Shazia F, Edmond Jane C, Suelflow Josh R, Coats David K, Yen Kimberly G
机构信息
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas; Department of Surgery, Division of Ophthalmology, Texas Children's Hospital, Houston, Texas.
Department of Ophthalmology, Dell Medical School, University of Texas at Austin.
出版信息
J AAPOS. 2019 Aug;23(4):232-234. doi: 10.1016/j.jaapos.2019.04.004. Epub 2019 May 30.
Band keratopathy is a corneal degeneration caused by chronic inflammation, systemic abnormalities, or, rarely, a primary biallelic SLC4A4 mutation leading to calcium hydroxyapatite deposition in Bowman's layer. We report a series of 16 eyes of 10 children with a remote history of diode laser treated retinopathy of prematurity who developed late-onset band keratopathy without evidence of other prior risk factors. The majority of patients developed band keratopathy bilaterally. Five eyes had visually significant central band keratopathy that required treatment with disodium ethylenediaminetetracetic acid (EDTA) chelation or phototherapeutic keratectomy. Band keratopathy may be an underreported late ophthalmic complication of diode-laser treated retinopathy of prematurity.
带状角膜病变是一种由慢性炎症、全身异常引起的角膜变性，或很少由原发性双等位基因SLC4A4突变导致羟基磷灰石钙沉积于Bowman层所致。我们报告了10名儿童的16只眼，这些儿童有二极管激光治疗早产儿视网膜病变的既往史，出现了迟发性带状角膜病变，且无其他先前危险因素的证据。大多数患者双侧发生带状角膜病变。5只眼有导致视力显著下降的中央带状角膜病变，需要用乙二胺四乙酸二钠（EDTA）螯合或光治疗性角膜切除术进行治疗。带状角膜病变可能是二极管激光治疗早产儿视网膜病变未被充分报道的晚期眼部并发症。
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