Mazzoli Livia S, Urata Carla N, Kasahara Niro
Irmandade da Santa Casa de Misericordia de Sao Paulo, Rua Sao Mauro, 292, Sao Paulo, SP, 02526-050, Brazil.
Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil.
Graefes Arch Clin Exp Ophthalmol. 2019 Sep;257(9):1941-1946. doi: 10.1007/s00417-019-04380-5. Epub 2019 Jun 1.
Older people present significant declines in face recognition with age. Spatial vision (high-contrast acuity) and age are the best predictors of face recognition. Visual disabilities are more common in the older population due to aging eye diseases. The purpose of the study was to compare the face recognition memory deficit between primary open angle glaucoma (POAG) and age-related macular degeneration (ARMD) patients living in a developing country.
This was a cross-sectional, observational study. The sample comprised 64 patients with POAG, 48 with ARMD, and 52 controls. All groups were matched for age, gender, comorbidity, and ethnic distribution. Evidence of cognitive impairment was ruled out and subjects with even mild cognitive impairment were not included in the study. After a complete eye examination including measurement of the best-corrected visual acuity, fundus evaluation, and automated visual field, all subjects underwent the Cambridge face memory test (CFMT). CFMT score in percentage (%) was the main outcome measure and data were compared with ANOVA.
The mean age was 66.6 ± 9.2, 69.8 ± 9.3, and 63.4 ± 7.3 years, for POAG, ARMD, and controls, respectively (P = 0.152). Gender, ethnicity, and comorbidity were evenly distributed among the groups. The CFMT score was 53.3 ± 15.2%, 49.8 ± 14.2%, and 62.1 ± 15.9% for POAG, ARMD, and controls, respectively (P < 0.001).
ARMD and POAG patients have higher face recognition memory deficit as compared to normal controls. This might be due to a visual disability.
老年人的面部识别能力会随着年龄增长而显著下降。空间视觉（高对比度视力）和年龄是面部识别的最佳预测因素。由于老年性眼病，视觉障碍在老年人群中更为常见。本研究的目的是比较发展中国家原发性开角型青光眼（POAG）和年龄相关性黄斑变性（ARMD）患者之间的面部识别记忆缺陷。
这是一项横断面观察性研究。样本包括64例POAG患者、48例ARMD患者和52例对照。所有组在年龄、性别、合并症和种族分布方面进行了匹配。排除了认知障碍的证据，即使有轻度认知障碍的受试者也未纳入研究。在进行包括最佳矫正视力测量、眼底评估和自动视野检查在内的全面眼部检查后，所有受试者均接受了剑桥面部记忆测试（CFMT）。CFMT得分以百分比（%）表示，是主要结局指标，数据采用方差分析进行比较。
POAG组、ARMD组和对照组的平均年龄分别为66.6±9.2岁、69.8±9.3岁和63.4±7.3岁（P = 0.152）。性别、种族和合并症在各组中分布均匀。POAG组、ARMD组和对照组的CFMT得分分别为53.3±15.2%、49.8±14.2%和62.1±15.9%（P < 0.001）。
与正常对照组相比，ARMD和POAG患者的面部识别记忆缺陷更高。这可能是由于视觉障碍所致。
