Department of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
H.E.J. Research Institute of Chemistry, ICCBS, University of Karachi, Karachi, 75270, Pakistan.
Mol Divers. 2020 May;24(2):455-462. doi: 10.1007/s11030-019-09966-z. Epub 2019 Jun 1.
A new application of α-alkoxymethylphosphonium salts in the nucleophilic phenylation of carbonyl compounds is demonstrated. Phenylation of aldehydes, ketones and acyl halides were studied by employing α-alkoxymethyltriphenylphosphonium halides in the presence of lithium hydroxide. New application of α-alkoxymethyltriphenylphosphonium salts. Metal-free, mild and selective phenylation. Easy preparation and handling of the reagent.
本文展示了α-烷氧基甲基膦盐在羰基化合物的亲核芳基化反应中的新应用。通过使用α-烷氧基甲基三苯基卤化膦在氢氧化锂的存在下，研究了醛、酮和酰卤的芳基化反应。α-烷氧基甲基三苯基膦盐的新应用。无金属、温和、选择性的芳基化。试剂的制备和处理简单。
