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[大鼠小脑发育过程中内源性凝集素的免疫细胞化学定位]

[Immunocytochemical localization of endogenous lectin during the development of the cerebellum in the rat].

作者信息

Kuchler S, Vincendon G, Zanetta J P

机构信息

Centre de Neurochimie du C.N.R.S., Unité 44 de l'I.N.S.E.R.M., Strasbourg.

出版信息

C R Acad Sci III. 1987;305(8):317-20.

PMID:3115503
Abstract

An endogenous cerebellar lectin (called CSL) was localized immunocytochemically using antibodies against the antigen. It was found that the lectin is not specifically localized in one of the nervous cell types. This compound, intracellularly localized in adult tissue, accumulated in the cerebellar premigratory zone and in white matter of young rats, suggesting the involvement of this molecule in contact guidance of cell migration and in myelination.

摘要

一种内源性小脑凝集素(称为CSL)使用针对该抗原的抗体进行了免疫细胞化学定位。发现该凝集素并非特异性地定位于某一种神经细胞类型。这种在成年组织中定位于细胞内的化合物,在幼鼠的小脑迁移前区和白质中积累,提示该分子参与细胞迁移的接触导向和髓鞘形成。

相似文献

1
[Immunocytochemical localization of endogenous lectin during the development of the cerebellum in the rat].[大鼠小脑发育过程中内源性凝集素的免疫细胞化学定位]
C R Acad Sci III. 1987;305(8):317-20.
2
An endogenous lectin found in rat astrocyte cultures has a role in cell adhesion but not in cell proliferation.
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引用本文的文献

1
Lectin-binding patterns in the development of the cerebellum.小脑发育过程中的凝集素结合模式。
Anat Embryol (Berl). 1994 Feb;189(2):169-79. doi: 10.1007/BF00185775.
2
An endogenous lectin and one of its neuronal glycoprotein ligands are involved in contact guidance of neuron migration.
Proc Natl Acad Sci U S A. 1990 Aug;87(16):6455-9. doi: 10.1073/pnas.87.16.6455.