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医疗保健向个性化医疗的转变——机遇与挑战。

Healthcare Transformation Towards Personalized Medicine - Chances and Challenges.

作者信息

Blobel Bernd, Ruotsalainen Pekka

机构信息

Medical Faculty, University of Regensburg, Germany.

Faculty of Information Technology and Communication Sciences (ITC), Tampere University, Finland.

出版信息

Stud Health Technol Inform. 2019;261:3-21.

PMID:31156085
Abstract

The paper introduces a structured approach to transforming healthcare towards personalized, preventive, predictive, participative precision (P5) medicine. It highlights the promising methodological paradigm changes, accompanied by related organizational and technological ones. In the latter context, the deployment of artificial intelligence and autonomous systems is crucial beside miniaturization and mobility. Beside their opportunities, those advanced technologies also bear risks to be managed. Beside the relationships between technology and human actors, the behavior of intelligent and autonomous systems from a humanistic and ethical perspective is in the center of considerations. The different existing approaches for guaranteeing the intended properties are presented and compared for deriving a common set of necessary principles to be met for P5 medicine.

摘要

本文介绍了一种将医疗保健转变为个性化、预防性、预测性、参与性精准(P5)医学的结构化方法。它强调了有前景的方法学范式转变,以及相关的组织和技术转变。在后一种情况下,除了小型化和移动性之外,人工智能和自主系统的部署至关重要。这些先进技术除了带来机遇外,也存在需要管理的风险。除了技术与人类行为者之间的关系外,从人文和伦理角度看待智能和自主系统的行为也是考虑的核心。文中介绍并比较了现有的不同方法,以确保实现预期特性,从而得出一套P5医学必须满足的共同必要原则。

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