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社论评论:考虑骨髓抽吸浓缩物在膝关节软骨缺损修复中的临床应用?这是一种干细胞治疗吗?

Editorial Commentary: Considering Clinical Application of Bone Marrow Aspirate Concentrate for Restoration of Cartilage Defects in the Knee? Is It a Kind of Stem Cell Therapy?

机构信息

Sungkyunkwan University.

Chung-Ang University.

出版信息

Arthroscopy. 2019 Jun;35(6):1878-1879. doi: 10.1016/j.arthro.2019.03.008.

DOI:10.1016/j.arthro.2019.03.008
PMID:31159970
Abstract

The role of bone marrow aspirate concentrate (BMAC) is still inconclusive for restoration of chondral defects in lesions of the knee. More investigation is needed; thus, clinical application of BMAC for chondral defects should be considered cautiously. Correct nomenclature of the entity of cells used in various stem cell therapies for the treatment of cartilage lesions is critical to properly assess the efficacy and safety of various stem cell therapies. Constant effort is needed to prove the therapeutic potential of various novel therapeutic options such as BMAC or stem cell therapy under correct terminology for cartilage restoration before routine clinical application.

摘要

骨髓抽吸浓缩物(BMAC)在膝关节软骨缺损修复中的作用仍不明确。需要进一步研究;因此,对于软骨缺损,BMAC 的临床应用应谨慎考虑。正确命名各种用于治疗软骨损伤的干细胞疗法中使用的细胞实体对于正确评估各种干细胞疗法的疗效和安全性至关重要。在常规临床应用之前,需要不断努力证明 BMAC 或干细胞疗法等各种新的治疗选择在正确的术语下用于软骨修复的治疗潜力。

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