The Johns Hopkins Surgery Center for Outcomes Research (JSCOR), Johns Hopkins School of Medicine, Baltimore, Md.
Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University School of Medicine, Baltimore, Md.
J Vasc Surg. 2019 Jun;69(6):1863-1873.e1. doi: 10.1016/j.jvs.2018.08.182.
The overall use of intensive care units (ICUs) in the United States has been steadily increasing and is associated with tremendous health care costs. We suspect that the burden of ICU utilization after elective infrainguinal lower extremity bypass (LEB) procedures is high, despite relatively low risks of complications in the immediate postoperative period. We sought to identify the burden of ICU utilization after elective LEB in patients with claudication.
We queried the Premier Healthcare Database for all adult patients undergoing first recorded elective infrainguinal LEB for claudication from 2009 to 2015. Baseline characteristics and ICU utilization on postoperative day 0 (POD 0) were identified for each patient using Premier room and board chargemaster codes. A bivariate logistic regression was performed and postestimation concordance statistics were calculated to identify predictors of postoperative ICU vs regular surgical floor admission immediately after surgery.
There were 6010 patients who met the selection criteria, of whom 2772 (46.1%) were admitted to the ICU and 3238 (53.9%) to the regular surgical floor on POD 0. Whereas patient-level factors were responsible for minor differences found in postoperative admission to the ICU after elective LEB, hospital characteristics made up the majority of variation in admission practices. Specifically, patients undergoing elective infrainguinal LEB in rural, nonteaching, small hospitals and those in certain geographic regions were more likely to be admitted to the ICU than to the floor (all, P < .001). Patient-level factors were poorly predictive of admission to the ICU immediately postoperatively, with C statistics ranging from 0.50 to 0.53. In contrast, hospital-level factors had higher C statistics ranging from 0.51 to 0.66, with geographic location being the strongest predictor of post-LEB ICU admission. There were no significant differences in the incidence of postoperative wound complications, major adverse limb events, major adverse cardiac events, or in-hospital mortality between groups (all, P ≥ .32). The median total hospital cost was $2340 higher for ICU compared with floor admission ($13,273 [interquartile range, $10,136-$17,883] vs $10,927 [interquartile range, $8342-$14,523]; P < .001).
Nearly half of patients are admitted to an ICU directly after elective infrainguinal LEB for claudication. This practice is associated with significantly higher hospital cost and is predominantly influenced by hospital-level rather than by patient-level factors. Perioperative morbidity and mortality were similar regardless of postoperative disposition. To minimize ICU utilization, postoperative care intensity should be determined by clinical severity of the patient rather than by hospital routine.
美国重症监护病房(ICU)的整体使用率一直在稳步上升,与之相关的医疗保健费用也非常高。我们推测,尽管术后早期并发症的风险相对较低,但择期下肢动静脉旁路(LEB)术后 ICU 的使用负担仍然很高。我们试图确定在有跛行的患者中,择期 LEB 术后 ICU 使用的负担。
我们从 2009 年至 2015 年,在 Premier Healthcare Database 中查询了所有接受第一次记录的择期下肢动静脉旁路(LEB)治疗跛行的成年患者。使用 Premier 病房和董事会计费主代码确定每位患者术后第 0 天(POD0)的基本特征和 ICU 使用情况。进行了双变量逻辑回归,然后进行了后估计一致性统计,以确定术后 ICU 与术后立即接受常规外科病房治疗的预测因素。
符合选择标准的患者有 6010 人,其中 2772 人(46.1%)在 POD0 入住 ICU,3238 人(53.9%)入住常规外科病房。虽然患者因素导致术后接受择期 LEB 后 ICU 入住率存在较小差异,但医院特征构成了入住实践差异的主要部分。具体来说,在农村、非教学、小医院接受择期下肢动静脉旁路手术的患者和在某些地理区域的患者更有可能入住 ICU,而不是病房(均,P<.001)。患者因素对术后立即入住 ICU 的预测作用较差,C 统计值范围为 0.50 至 0.53。相比之下,医院因素的 C 统计值较高,范围为 0.51 至 0.66,地理位置是术后 LEB ICU 入住的最强预测因素。两组之间在术后伤口并发症、主要肢体不良事件、主要心脏不良事件或住院死亡率方面无显著差异(均,P≥.32)。与普通病房相比,ICU 住院总费用中位数高 2340 美元(分别为 13273 美元[四分位距,10136-17883 美元]和 10927 美元[四分位距,8342-14523 美元];P<.001)。
近一半的患者在接受有跛行的择期下肢动静脉旁路术后直接入住 ICU。这种做法与显著较高的医院费用有关,主要受医院水平因素而不是患者水平因素的影响。术后发病率和死亡率与术后处理无关。为了最大限度地减少 ICU 的使用,术后护理强度应根据患者的临床严重程度来确定,而不是根据医院的常规来确定。