Bristol-Myers Squibb, Uxbridge, UB8 1DH, UK.
Evidera, London, W6 8BJ, UK.
Future Oncol. 2019 Jul;15(21):2471-2477. doi: 10.2217/fon-2019-0150. Epub 2019 Jun 4.
In the UK, there are limited data sources for evaluating real-world research questions related to oncology therapy. We conducted a pilot study to investigate the feasibility of extracting data directly from a chemotherapy prescription platform (ChemoCare) utilized in standard care. Concordance was compared with data extracted manually for patients with advanced melanoma as part of a concurrent chart review (gold-standard) using Cohen's kappa and the intraclass correlation coefficient. There was high concordance between data automatically extracted from the prescription platform and chart review data. This pilot can be used as a framework for future studies using direct, automated extraction from prescription platforms.
在英国，评估与肿瘤治疗相关的真实世界研究问题的数据源有限。我们进行了一项试点研究，以调查直接从化疗处方平台（ChemoCare）提取数据的可行性，该平台用于标准护理。使用 Cohen 的 Kappa 和组内相关系数，比较了与同时进行的图表审查（金标准）中提取的晚期黑色素瘤患者的手动数据的一致性。从处方平台自动提取的数据与图表审查数据之间具有高度一致性。该试点研究可作为未来使用处方平台进行直接自动提取的研究的框架。
