Song S P, Li W W, Ma X L
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun;33(6):572-576. doi: 10.13201/j.issn.1001-1781.2019.06.025.
Squamous epithelial hyperplasia, cell apoptosis and bone destruction were thought to be three key mechanisms in the pathogenesis of middle ear cholesteatoma. At present, the research on the pathogenesis of middle ear cholesteatoma mainly focuses on these three major pathological events. Studies have shown that various apoptosis-related genes and regulatory factors are associated with the development of cholesteatoma.
鳞状上皮增生、细胞凋亡和骨质破坏被认为是中耳胆脂瘤发病机制中的三个关键机制。目前，关于中耳胆脂瘤发病机制的研究主要集中在这三个主要病理事件上。研究表明，各种凋亡相关基因和调节因子与胆脂瘤的发生发展有关。
