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严重难治性心力衰竭合并急性心肌梗死时的动脉反搏

Arterial counterpulsation in severe refractory heart failure complicating acute myocardial infarction.

作者信息

O'Rourke M F, Sammel N, Chang V P

出版信息

Br Heart J. 1979 Mar;41(3):308-16. doi: 10.1136/hrt.41.3.308.

Abstract

The role of arterial counterpulsation was sought in 100 patients with severe refractory cardiac failure complicating myocardial infarction. Seventy-four were in shock and 26 were not. Average duration of counterpulsation was 7.0 days. Hospital survival was 34 per cent (25/74) in shock (predicted less than 10%) and 65 per cent in patients who were not in shock (predicted less than 50%). Survival at 4 years was 10 +/- 4 per cent in shock and 37 +/- 11 per cent in patients not in shock; functional status was class 1 or 2 in 5 of 9 patients in shock and in 8 of 12 survivors not in shock. Results were best when counterpulsation was started early after onset of symptoms, when ischaemic pain was still present, or when a mechanical defect was corrected surgically. Early coronary artery bypass surgery performed alone in 9 patients did not influence survival or functional status. Complications of counterpulsation occurred in 17 patients in shock and in 2 patients not in shock, all but 6 on the first day; none directly caused death. Counterpulsation is an effective and safe adjunct to medical treatment of complicated infarction provided the intervention is prompt.

摘要

在100例并发心肌梗死的严重难治性心力衰竭患者中探索了动脉反搏的作用。其中74例处于休克状态,26例未休克。反搏的平均持续时间为7.0天。休克患者的住院生存率为34%(25/74)(预计低于10%),未休克患者的住院生存率为65%(预计低于50%)。休克患者4年生存率为10±4%,未休克患者为37±11%;休克的9例患者中有5例、未休克的12例幸存者中有8例功能状态为1级或2级。当在症状发作后早期、缺血性疼痛仍存在或机械性缺陷经手术纠正时开始反搏,结果最佳。9例单独进行早期冠状动脉搭桥手术的患者,其生存率或功能状态未受影响。17例休克患者和2例未休克患者出现反搏并发症,除6例外均在第一天出现;无一例直接导致死亡。如果干预及时,反搏是治疗复杂性梗死的一种有效且安全的辅助治疗方法。

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本文引用的文献

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REGULATION OF CORONARY BLOOD FLOW.冠状动脉血流的调节
Physiol Rev. 1964 Jan;44:1-29. doi: 10.1152/physrev.1964.44.1.1.
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Technique of femoral artery cannulation for phase-shift balloon pumping.
J Thorac Cardiovasc Surg. 1968 Aug;56(2):219-20.
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Cardiogenic shock. A review of one year's experience.心源性休克。一年经验回顾。
Med J Aust. 1971 May 8;1(19):1000-4. doi: 10.5694/j.1326-5377.1971.tb88005.x.
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Phase-shift balloon pumping in medically refractory cardiogenic shock. Results in 27 patients.
Arch Surg. 1969 Dec;99(6):739-43. doi: 10.1001/archsurg.1969.01340180063013.

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