Department of Radiology, Yuan's General Hospital, Kaohsiung, Taiwan.
Post-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Eur J Cancer Care (Engl). 2019 Jul;28(4):e13064. doi: 10.1111/ecc.13064. Epub 2019 Jun 5.
To explore the effects of home-based music intervention (HBMI) on symptom severity, pain intensity and perceived fatigue among patients with breast cancer. In this randomised controlled trial, patients with breast cancer were randomly assigned into an HBMI or control group. The HBMI group was administered 24-week HBMI involving five 30-min sessions per week. The primary outcome was symptom severity; the secondary outcomes were pain and fatigue. A generalised estimating equation was employed to compare the effects after 6, 12 and 24 weeks of intervention between the two groups. A total of 60 patients were recruited. After 6, 12 and 24 weeks, HBMI significantly reduced symptom severity, pain intensity, overall fatigue, general fatigue, emotional fatigue and vigour (p < 0.05). Additionally, HBMI significantly reduced physical fatigue after 6 (p = 0.003) and 12 (p = 0.013) weeks and mental fatigue after 6 weeks (p = 0.001). After 6, 12 and 24 weeks, HBMI reduced symptom severity, pain intensity and overall fatigue. Furthermore, HBMI instantaneously reduced physical and mental fatigue. We recommend that HBMI be administered to patients with breast cancer to reduce their negative thoughts associated with cancer.
探讨基于家庭的音乐干预（HBMI）对乳腺癌患者症状严重程度、疼痛强度和感知疲劳的影响。在这项随机对照试验中，将乳腺癌患者随机分为 HBMI 组或对照组。HBMI 组接受为期 24 周的 HBMI，每周进行 5 次 30 分钟的干预。主要结局指标为症状严重程度；次要结局指标为疼痛和疲劳。采用广义估计方程比较两组干预后 6、12 和 24 周的效果。共纳入 60 例患者。6、12 和 24 周后，HBMI 显著降低了症状严重程度、疼痛强度、总体疲劳、一般疲劳、情绪疲劳和活力（p<0.05）。此外，HBMI 还显著降低了 6 周（p=0.003）和 12 周（p=0.013）时的躯体疲劳以及 6 周时的精神疲劳（p=0.001）。6、12 和 24 周后，HBMI 降低了症状严重程度、疼痛强度和总体疲劳。此外，HBMI 即刻降低了躯体和精神疲劳。我们建议对乳腺癌患者进行 HBMI，以减轻与癌症相关的负面想法。
