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阳痿:通过血管活性药物自体注射进行治疗

Impotence: treatment by autoinjection of vasoactive drugs.

作者信息

Williams G, Mulcahy M J, Kiely E A

机构信息

Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.

出版信息

Br Med J (Clin Res Ed). 1987 Sep 5;295(6598):595-6. doi: 10.1136/bmj.295.6598.595.

DOI:10.1136/bmj.295.6598.595
PMID:3117249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1248757/
Abstract

One hundred and twenty five men with psychogenic or organic impotence used autoinjection of the penile corpora cavernosa with either papaverine or papaverine and phentolamine for a mean period of 10.5 months (range 1-24 months) to achieve penile erection for sexual intercourse. Prolonged (over four hours) painless erection resulted from 34 of the 3513 self administered injections. This seems to be a highly effective approach to treating impotence irrespective of the aetiology.

摘要

125名患有心因性或器质性阳痿的男性使用罂粟碱或罂粟碱与酚妥拉明对阴茎海绵体进行自我注射,平均持续10.5个月(范围1 - 24个月),以实现性交时的阴茎勃起。在3513次自我注射中,有34次导致了持续(超过4小时)的无痛勃起。无论病因如何,这似乎都是一种治疗阳痿的高效方法。

相似文献

1
Impotence: treatment by autoinjection of vasoactive drugs.阳痿:通过血管活性药物自体注射进行治疗
Br Med J (Clin Res Ed). 1987 Sep 5;295(6598):595-6. doi: 10.1136/bmj.295.6598.595.
2
[Intracavernous pharmacotherapy for treatment and evaluation of impotence].[阴茎海绵体内药物治疗用于阳痿的治疗与评估]
Harefuah. 1991 Oct;121(7-8):223-5.
3
[Intracavernous injection of vasoactive drugs for treating erectile impotence].[海绵体内注射血管活性药物治疗勃起功能障碍]
Hinyokika Kiyo. 1988 Feb;34(2):301-4.
4
The use of vasoactive agents in the treatment of erectile impotence.血管活性药物在勃起功能障碍治疗中的应用。
N C Med J. 1990 Jun;51(6):295-6.
5
Intracavernous drug-induced erections in the management of male erectile dysfunction: experience with 100 patients.阴茎海绵体内注射药物治疗男性勃起功能障碍:100例患者的经验
J Urol. 1986 Apr;135(4):704-6. doi: 10.1016/s0022-5347(17)45825-3.
6
[Action of vasoactive drugs in male sexual impotence].[血管活性药物在男性性功能障碍中的作用]
Arch Esp Urol. 1989 Nov-Dec;42(9):900-4.
7
[Intracavernous pharmacotherapy for organic impotence in the elderly].[老年器质性阳痿的海绵体内药物治疗]
Harefuah. 1990 Aug;119(3-4):66-7.
8
Diagnostic and therapeutic technology assessment. Vasoactive intracavernous pharmacotherapy for impotence: papaverine and phentolamine.诊断与治疗技术评估。阴茎海绵体内血管活性药物疗法治疗阳痿:罂粟碱和酚妥拉明。
JAMA. 1990 Aug 8;264(6):752-4.
9
Penile response to intracavernosal vasoactive intestinal polypeptide alone and in combination with other vasoactive agents.阴茎对单独使用以及与其他血管活性药物联合使用的海绵体内血管活性肠肽的反应。
Br J Urol. 1989 Aug;64(2):191-4. doi: 10.1111/j.1464-410x.1989.tb05986.x.
10
Intracavernous self-injection for impotence: a long-term therapeutic option? Experience in 78 patients.阴茎海绵体内自我注射治疗阳痿:一种长期治疗选择?78例患者的经验
J Urol. 1988 Nov;140(5):972-4. doi: 10.1016/s0022-5347(17)41902-1.

引用本文的文献

1
Intracavernous pharmacotherapy.海绵体内药物治疗。
World J Urol. 1997;15(1):71-7. doi: 10.1007/BF01275160.
2
Optimal treatment of erectile failure in patients with diabetes.糖尿病患者勃起功能障碍的最佳治疗方法。
Drugs. 1995 Apr;49(4):548-54. doi: 10.2165/00003495-199549040-00005.
3
Medical treatment of impotence with papaverine and phentolamine intracavernosal injection.采用罂粟碱和酚妥拉明海绵体内注射治疗阳痿。
Ulster Med J. 1990 Oct;59(2):174-6.

本文引用的文献

1
Penile flow index utilizing a Doppler pulse wave analysis to identify penile vascular insufficiency.利用多普勒脉搏波分析来识别阴茎血管功能不全的阴茎血流指数。
J Urol. 1980 May;123(5):669-73. doi: 10.1016/s0022-5347(17)56082-6.
2
Psychological aspects of male sexual dysfunction. Diagnosis and management.
Urol Clin North Am. 1981 Feb;8(1):135-42.
3
Complications of penile prosthesis surgery for impotence.阴茎假体植入治疗阳痿的并发症。
J Urol. 1982 Dec;128(6):1192-4. doi: 10.1016/s0022-5347(17)53418-7.
4
Treatment of vasculogenic sexual impotence by revascularizing cavernous and/or dorsal arteries using microvascular techniques.采用微血管技术对海绵体动脉和/或背动脉进行血管重建治疗血管源性勃起功能障碍。
Urology. 1982 Sep;20(3):271-5. doi: 10.1016/0090-4295(82)90636-7.
5
Microscopic penile revascularization.显微阴茎血管重建术。
J Urol. 1983 Mar;129(3):517-21. doi: 10.1016/s0022-5347(17)52211-9.
6
Practical diagnostic screening for impotence.阳痿的实用诊断筛查
Urology. 1984 May;23(5 Spec No):98-102. doi: 10.1016/0090-4295(84)90251-6.
7
The inflatable penile prosthesis, reoperation and patient satisfaction: a comparison of statistics obtained from patient record review with statistics obtained from intensive followup search.可膨胀阴茎假体、再次手术与患者满意度:对患者病历回顾所得统计数据与深入随访搜索所得统计数据的比较。
J Urol. 1984 May;131(5):894-5. doi: 10.1016/s0022-5347(17)50698-9.
8
Intracavernous injection of papaverine as a diagnostic and therapeutic method in erectile failure.
Angiology. 1984 Feb;35(2):79-87. doi: 10.1177/000331978403500203.
9
New treatment for priapism.阴茎异常勃起的新疗法。
Lancet. 1984 Jul 28;2(8396):220-1. doi: 10.1016/s0140-6736(84)90500-2.
10
Causes and classification of impotence.阳痿的病因及分类。
Urol Clin North Am. 1981 Feb;8(1):79-89.