Watanabe H, Nakao M, Nakagawa S, Takada H
Department of Urology, Kyoto Prefectural University of Medicine, Japan.
Cancer Chemother Pharmacol. 1987;20 Suppl:S49-51. doi: 10.1007/BF00262485.
The clinical results obtained in 81 cases of bladder tumor are used as a basis for discussion of factors influencing the effect of bladder instillation therapy. The following conclusions are derived: 1) If bladder instillation therapy aims only at complete remission (CR), tumors over 1 cm in diameter should be excluded, because this is the theoretical size limit beyond which instillation therapy cannot lead to CR. 2) At least 40 ml of drugs may be needed for instillation therapy for tumors located in area B, the limited part posterior to the trigonum.
以81例膀胱肿瘤的临床结果为依据，讨论影响膀胱灌注治疗效果的因素。得出以下结论：1）如果膀胱灌注治疗仅旨在实现完全缓解（CR），直径超过1cm的肿瘤应排除在外，因为这是理论上的大小界限，超过此界限灌注治疗无法导致完全缓解。2）对于位于B区（三角区后方有限部分）的肿瘤，灌注治疗可能至少需要40ml药物。
