Lainiala Olli S, Reito Aleksi P, Nieminen Jyrki J, Eskelinen Antti P
Coxa Hospital for Joint Replacement, Tampere, Finland; Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland.
J Arthroplasty. 2019 Sep;34(9):2058-2064.e1. doi: 10.1016/j.arth.2019.04.058. Epub 2019 May 2.
Adverse reactions to metal debris (ARMD) have been a problem with metal-on-metal (MoM) hip systems for a decade. Unacceptably high revision rates have been described for both stemmed MoM total hip arthroplasties (THAs) and hip resurfacings. The aim of this study was to report survivorship and temporal trends of hip revisions in patients with MoM hips.
We identified 2520 patients with 3013 MoM hip arthroplasties performed at our institution. These included 1532 primary stemmed MoM THAs, 1262 MoM hip resurfacings, and 219 stemmed MoM THAs implanted in revision surgery.
Revision surgery was performed on 551 (36%) primary stemmed MoM THAs and on 179 (14%) resurfacings. The most common reason for revision was ARMD both among primary MoM THAs (83%) and hip resurfacings (70%). The 15-year implant survivorship was 69% (95% confidence interval [CI] 67-71%) for the whole study group, 56% (CI 53-60%) for stemmed primary MoM THAs, and 84% (CI 82-87%) for hip resurfacings. Clear temporal peak in the number of revisions for ARMD was seen in 2011-2013, and the trend has been decreasing since.
After a decade since outburst of the ARMD problematics with MoM hips, a large proportion of them have gone through revision surgery at our single high-volume center. The peak years were 2011-2013, and thereafter, the number of ARMD revisions has decreased every year. With the threshold for revision remaining constant at our institution, it is not likely that large amount of new cases of ARMD will be seen. As these results are derived from a single center's data, similar studies from other institutions are needed to see whether our results represent a global trend.
金属对金属(MoM)髋关节系统出现金属碎片不良反应(ARMD)问题已有十年。带柄MoM全髋关节置换术(THA)和髋关节表面置换术的翻修率高得令人难以接受。本研究旨在报告MoM髋关节患者髋关节翻修的生存率及时间趋势。
我们确定了在本机构接受3013例MoM髋关节置换术的2520例患者。其中包括1532例初次带柄MoM THA、1262例MoM髋关节表面置换术以及219例在翻修手术中植入的带柄MoM THA。
551例(36%)初次带柄MoM THA和179例(14%)表面置换术进行了翻修手术。翻修的最常见原因在初次MoM THA组(83%)和髋关节表面置换术组(70%)中均为ARMD。整个研究组15年植入物生存率为69%(95%置信区间[CI] 67 - 71%),初次带柄MoM THA为56%(CI 53 - 60%),髋关节表面置换术为84%(CI 82 - 87%)。2011 - 2013年出现了ARMD翻修数量的明显时间峰值,此后呈下降趋势。
MoM髋关节出现ARMD问题十年后,在我们这个高手术量的单一中心,很大一部分患者接受了翻修手术。高峰期为2011 - 2013年,此后,ARMD翻修数量每年都在减少。鉴于我们机构的翻修阈值保持不变,不太可能出现大量新的ARMD病例。由于这些结果来自单一中心的数据,需要其他机构进行类似研究,以确定我们的结果是否代表全球趋势。