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病例报告:金属对金属髋关节置换术后炎性假瘤的形成与复发

Case report: Formation and recurrence of inflammatory pseudotumor after metal-on-metal hip arthroplasty.

作者信息

Min Meipeng, Xing Chenyang, Xu Peili, Wei Xincheng, Fan Lei

机构信息

Department of Orthopedics, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Front Med (Lausanne). 2024 Jul 11;11:1422230. doi: 10.3389/fmed.2024.1422230. eCollection 2024.

Abstract

The metal-on-metal (MoM) artificial hip joint is a prosthesis used in early hip arthroplasty, particularly for hip resurfacing and total hip arthroplasty. However, abrasion and corrosion of MoM bearings result in the production of metal ions, such as cobalt and chromium, thereby inducing several complications such as inflammatory pseudotumor, aseptic inflammation, and allergy to metal ions (delayed type IV hypersensitivity). In this case report, we present a patient who was hospitalized for recurrence of a mass in the right inguinal area. In 2010, the patient underwent right MoM total hip arthroplasty for right femoral head necrosis and exhibited a good postoperative recovery. In 2019, the patient experienced pain in the right hip with activity limitation without any evident triggers, and a palpable mass was observed in the right inguinal area. A large periprosthetic mass was resected under general anesthesia, and the patient recovered well after the operation. Based on post-surgery imaging and pathological examinations, the mass was diagnosed as a periprosthetic inflammatory pseudotumor. In 2021, the inflammatory pseudotumor recurred at the same site. He then underwent right total hip revision surgery under epidural anesthesia and recovered well after surgery. No recurrence was noted at moderate follow-up. The incidence of inflammatory pseudotumors is high in MoM hip arthroplasty. Early revision is necessary in patients who meet the indications for revision, while regular postoperative follow-up is crucial.

摘要

金属对金属(MoM)人工髋关节是早期髋关节置换术中使用的一种假体,尤其用于髋关节表面置换和全髋关节置换。然而,MoM关节轴承的磨损和腐蚀会导致金属离子(如钴和铬)的产生,从而引发多种并发症,如炎性假瘤、无菌性炎症和金属离子过敏(迟发型IV型超敏反应)。在本病例报告中,我们介绍了一名因右腹股沟区肿物复发而住院的患者。2010年,该患者因右侧股骨头坏死接受了右MoM全髋关节置换术,术后恢复良好。2019年,患者无明显诱因出现右髋部疼痛及活动受限,右腹股沟区可触及肿物。在全身麻醉下切除了一个较大的假体周围肿物,术后患者恢复良好。根据术后影像学和病理检查,该肿物被诊断为假体周围炎性假瘤。2021年,炎性假瘤在同一部位复发。随后,他在硬膜外麻醉下接受了右全髋关节翻修手术,术后恢复良好。在中期随访中未发现复发。MoM髋关节置换术中炎性假瘤的发生率较高。符合翻修指征的患者有必要早期翻修,而术后定期随访至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed3e/11269118/5c2aee06e036/fmed-11-1422230-g001.jpg

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